This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Both of these medicines depress the central nervous system (CNS).
What might happen:
Concurrent use can result in extreme sleepiness, slowed or difficult breathing, coma, or death.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together and how long you have been taking an opioid. Seek medical attention immediately if you develop unusual dizziness or lightheadedness, extreme sleepiness, slowed or difficult breathing, or unresponsiveness.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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