XELJANZ Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • a bacterial infection
  • shingles
  • an infection
  • pneumonia
  • cellulitis

If experienced, these tend to have a Less Severe expression i

  • high cholesterol
  • excessive fat in the blood
  • throat irritation
  • a common cold
  • urinary tract infection
  • headache

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • an infection due to a virus
  • opportunistic fungal infection
  • anemia
  • high blood pressure
  • inflammation of the lining of the stomach and intestines
  • abnormal liver function tests

If experienced, these tend to have a Less Severe expression i

  • a skin rash

RARE side effects

If experienced, these tend to have a Severe expression i

  • active tuberculosis
  • an infection by the bacteria Listeria monocytogenes
  • an infection due to unusual mycobacteria
  • mononucleosis, the kissing disease
  • an unusual viral infection called cytomegalovirus infection
  • a fungal infection in the esophagus due to Candida
  • a type of systemic fungal infection called coccidioidomycosis
  • a type of fungal lung infection called histoplasmosis
  • infection with Cryptococcus fungus
  • pneumonia with a fungus called Pneumocystis jirovecii
  • cancer or malignancy
  • lung cancer
  • squamous cell carcinoma
  • low levels of a type of white blood cell called neutrophils
  • increased lymphocyte cells in the blood
  • a decreased number of lymphocytes in the blood
  • a heart attack
  • a clot in the lung
  • chronic heart failure
  • obstruction of a blood vessel by a blood clot
  • a blood clot in an artery
  • a blood clot
  • blood clot in a deep vein of the extremities
  • diverticulitis
  • enlarged fatty liver
  • nephrotic syndrome, a type of kidney disorder
  • a type of allergic reaction called angioedema
  • malignant lymphoma
  • a rupture in the wall of the stomach or intestine
  • lung tissue problem
  • reactivation of hepatitis B infection
  • kidney problems due to BK polyomavirus
  • a type of significant allergic skin reaction called DRESS syndrome

If experienced, these tend to have a Less Severe expression i

  • dehydration
  • inflammation of the tissue lining the sinuses
  • a type of stomach irritation called gastritis
  • indigestion
  • itching
  • joint pain
  • inflammation of a tendon
  • difficulty sleeping
  • fever
  • low energy
  • fluid retention in the legs, feet, arms or hands
  • weight gain
  • trouble breathing
  • cough
  • nausea
  • vomiting
  • a feeling of pins and needles on skin
  • intense abdominal pain
  • pain in the muscles or bones

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.