OLANZAPINE Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • personality disorders
  • a type of movement disorder called parkinsonism
  • a feeling of restlessness with inability to sit still

If experienced, these tend to have a Less Severe expression i

  • a high prolactin level
  • lazy eye
  • orthostatic hypotension, a form of low blood pressure
  • a stuffy and runny nose
  • dry mouth
  • constipation
  • backache
  • drowsiness
  • inducing of a relaxed easy state
  • dizziness
  • low energy
  • muscle tremors
  • weight gain
  • increased hunger
  • headache
  • generalized weakness
  • a change in the ability to pay attention

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • an extreme sense of wellbeing called euphoria
  • tardive dyskinesia, a disorder characterized by involuntary movements of the face, mouth and tongue
  • extrapyramidal disease, a type of movement disorder
  • memory loss
  • mental status changes
  • fever
  • fluid retention in the legs, feet, arms or hands
  • chest pain

If experienced, these tend to have a Less Severe expression i

  • high blood pressure
  • low blood pressure
  • bruising under the skin
  • throat irritation
  • excessive saliva production
  • indigestion
  • urinary tract infection
  • the inability to have an erection
  • joint pain
  • an abnormal increase in muscle tone
  • muscle stiffness
  • pain in the arms or legs
  • difficulty sleeping
  • chills
  • abnormal manner of walking
  • visible water retention
  • excessive thirst
  • a type of speech disorder called dysarthria
  • cough
  • nausea
  • vomiting
  • involuntary leakage of urine
  • stomach cramps
  • abnormal liver function tests
  • nervousness
  • a feeling of pins and needles on skin
  • deep sleep or sleep for long periods
  • fast heartbeat

RARE side effects

If experienced, these tend to have a Severe expression i

  • a complication of diabetes with high blood ketone levels called diabetic ketoacidosis
  • diabetic hyperosmolar coma
  • diabetes
  • excessive fat in the blood
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • increased eosinophils in the blood
  • neuroleptic malignant syndrome, a reaction characterized by fever, muscle rigidity and confusion
  • disturbance in the ability of the eye to focus
  • a change in vision
  • a stroke
  • obstruction of a blood vessel by a blood clot
  • blocked bowels with decreased peristaltic movement
  • enlarged fatty liver
  • liver failure
  • inflammation of the liver called hepatitis
  • priapism, a prolonged erection of the penis
  • a problem with menstrual periods
  • skin rash with sloughing
  • a condition with muscle tissue breakdown called rhabdomyolysis
  • osteoporosis, a condition of weak bones
  • seizures
  • sleep apnea
  • a skin rash
  • puffy face from water retention
  • high amount of bilirubin in the blood
  • swollen lymph nodes
  • trouble breathing
  • difficulty swallowing
  • an inability to completely empty the bladder
  • high blood sugar
  • heat stroke
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • inflammation of the liver with stoppage of bile flow
  • problems with food passing through the esophagus
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • pancreatitis
  • abnormal muscle movements
  • a type of significant allergic skin reaction called DRESS syndrome
  • painful and involuntary movement of the eyes called oculogyric crisis

If experienced, these tend to have a Less Severe expression i

  • confusion
  • altered interest in having sexual intercourse
  • stuttering
  • widening of blood vessels
  • enlarged breasts
  • breastmilk production not associated with childbirth or nursing
  • breast pain
  • increased sensitivity of the skin to the sun
  • itching
  • hair loss
  • hives
  • nosebleed
  • an increased need to urinate often
  • restless legs syndrome, an extreme discomfort in the calf muscles when sitting or lying down

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.