This medication can cause trouble breathing in people with long-term (chronic) lung disease (such as asthma, chronic obstructive pulmonary disease-COPD). This medication should not be used by people with chronic lung problems. Tell your doctor right away if you have trouble breathing, shortness of breath, persistent cough, or wheezing.

Your doctor will check your lung function before you start using this medication. (See also Notes section.


Inhaled insulin powder is used with a proper diet and exercise program to control high blood sugar in people with diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke.This man-made insulin product is the same as human insulin. It replaces the insulin that your body would normally make. It is a short-acting insulin. It works by helping blood sugar (glucose) get into cells so your body can use it for energy. This product is absorbed into the blood through your lungs. It starts working faster and lasts for a shorter time than regular insulin injected under the skin. It is usually used in combination with a medium- or long-acting insulin product. This medication may also be used alone or with other oral diabetes drugs (such as metformin).

How to use Afrezza Cartridge With Inhaler

Read the Medication Guide and Instructions for Use Leaflet provided by your pharmacist before you start using inhaled insulin and each time you get a refill. Follow the illustrated directions for the proper use of this medication. If you have any questions, ask your doctor, diabetes educator, or pharmacist.

This medication comes in cartridges in a blister package. Do not try to open the cartridges. The inhaler opens the blister/cartridge containing the insulin powder, allowing the insulin to be inhaled. Bring the medication and inhaler to room temperature before using. Follow your doctor's directions carefully.

Inhale this medication by mouth at the beginning of a meal as directed by your doctor. Because inhaled insulin is fast-acting, not eating immediately after inhaling a dose of this insulin may lead to low blood sugar.

The dosage is based on your medical condition and response to treatment.

Do not change brands or types of insulin without directions on how to do so from your doctor.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.

Check your blood sugar regularly as directed by your doctor. Keep track of your results and share them with your doctor. This is very important in order to determine the correct insulin dose.

Tell your doctor if your condition does not improve or if it worsens (your blood sugar is too high or too low).

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.