Lomustine decreases bone marrow function, an effect (possibly fatal) that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, or cause easy bruising/bleeding. These side effects usually occur 4 to 6 weeks after your dose and may last for 1 to 2 weeks. Tell your doctor right away if you develop any of the following symptoms: unusual tiredness, pale skin, signs of infection (such as sore throat that doesn't go away, fever, chills), easy bruising/bleeding.
Your doctor will closely monitor you and perform weekly blood tests for at least 6 weeks after each dose. Your dose and any further treatment will be based on your blood tests. Due to serious side effects, do not take this medication more often than once every 6 weeks. Follow your doctor's instructions carefully.
How to use Gleostine
See also Warning section.
Take this medication by mouth as a single dose as directed by your doctor, usually once every 6 weeks. Your dose may consist of 2 or more different strengths/colors of capsules. To prevent nausea and vomiting, take this medication on an empty stomach at least 1 hour before or 2 to 3 hours after a meal with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise. Swallow the capsules whole.
The dosage is based on your medical condition, response to treatment, body size, and lab tests.
Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.
Wear rubber or latex gloves when you handle the capsules.
Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the capsules.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.