Rarely, brodalumab may cause serious mental/mood changes, including depression and suicidal thoughts/attempts. Get medical help right away if you have symptoms such as depression, anxiety, or thoughts of suicide.
To receive this medication, all doctors, pharmacists, and patients must understand, agree to, and carefully follow the requirements of the Siliq REMS Program. These requirements apply in the United States. If you live in Canada or any other country, consult your doctor and pharmacist for your country's regulations.
This medication is used to treat plaque psoriasis. Brodalumab belongs to a class of drugs known as monoclonal antibodies. It works by blocking a certain natural protein in your body (interleukin-17A) that may cause inflammation and swelling. Brodalumab treatment may lead to reduced plaque thickness, redness, and scaling.
How to use Siliq Syringe
Read the Medication Guide and Instructions for Use provided by your pharmacist before you start using brodalumab and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Before treatment with this medication, your doctor will test you for tuberculosis (TB). Your doctor should also monitor you for symptoms of TB during and after treatment with this drug. If needed, treatment for TB or other infections should be given before receiving this medication.
This medication is given by injection under your skin as directed by your doctor. The injection is given in the upper arms, thighs, or abdomen (except for a 2-inch area around your belly button). The dosage is based on your medical condition and response to treatment. Follow your doctor's instructions carefully.
If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. Wash your hands before using this medication. Remove the medication from the refrigerator 30 minutes before you inject it to allow it to reach room temperature. Do not warm up this medication any other way such as by heating in the microwave, placing in hot water, or leaving it in direct sunlight. Do not shake the medication. The medication should be clear or slightly yellow. Before using, check this product visually for cloudiness, particles, or discoloration. If you see any of these things, do not use the liquid. Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject into skin that is irritated, sore, bruised, red, hard, scarred, or affected by psoriasis. To lessen bruising, do not rub the injection site after a shot. Learn how to store and discard medical supplies safely. Do not reuse syringes.
Use this medication regularly to get the most benefit from it. It may help to mark your calendar with a reminder.
Tell your doctor if your condition does not get better or if it gets worse.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.