Warnings:

Baricitinib may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. The most common serious infections include pneumonia, shingles, and urinary tract infections. The risk for infections may be higher if you also take other drugs that suppress the immune system (such as methotrexate, corticosteroids). Tell your doctor right away if you have any signs of infection (such as a sore throat that doesn't go away, fever, chills, cough, painful/frequent urination, non-healing skin sores).

You should have a tuberculosis (TB) skin test before and during treatment with this medication. Tell your doctor if you have been near someone with tuberculosis or have lived or traveled in areas where certain fungal infections (such as coccidioidomycosis, histoplasmosis) are common. These areas include the Ohio and Mississippi River valleys and the southwestern United States.

Though it is very unlikely to occur, there may be a risk of developing cancer (such as lymphoma, skin cancer) with this medication. Tell your doctor right away if you develop symptoms such as fever that doesn't go away, unusual lumps/growths, unexplained weight loss, night sweats, change in appearance or size of moles, or unusual skin changes.

Baricitinib may rarely cause serious blood clots to form in the legs or lungs. Tell your doctor if you have a history of blood clots (such as deep vein thrombosis, pulmonary embolism). Get medical help right away if you develop symptoms of a blood clot, including shortness of breath/rapid breathing, chest pain, or pain/swelling/warmth in the groin/calf.

Uses

Baricitinib is used to treat rheumatoid arthritis. It helps decrease pain, tenderness, and swelling in the joints.Baricitinib is being studied for use in combination with another drug (remdesivir) to treat coronavirus disease (COVID-19). It is used in hospitalized patients who need supplemental oxygen (including patients on a mechanical ventilator). It has not been approved by the FDA or Health Canada to treat coronavirus disease. However, the FDA is allowing baricitinib to be used to treat coronavirus disease in human studies and for emergency use. If baricitinib is used to treat coronavirus disease, more information about the drug should be provided by the doctor from the Informed Consent form for a study or the FDA Fact Sheet for Patients, Parents and Caregivers for emergency use.

How to use Baricitinib Tablet

Read the Medication Guide provided by your pharmacist before you start taking baricitinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Tell your doctor if your condition does not get better or if it gets worse.

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.