This medication is used to treat a certain blood disorder (acquired thrombotic thrombocytopenic purpura-aTTP). It is used in combination with certain other treatments for this disorder (plasma exchange, immune suppressing medication). In aTTP, blood clots form in small blood vessels throughout the body. These clots can cause serious medical problems if they block vessels and limit or stop blood flow to organs such as the brain, kidneys, and heart. This disorder can also cause red blood cells to break apart faster than the body can replace them, which results in anemia. Caplacizumab works by causing your body to make fewer/smaller blood clots.
How to use Caplacizumab-Yhdp 11 Mg Solution For Injection
Read the Patient Information Leaflet if available from your pharmacist before you start using caplacizumab and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
The first dose of this medication is given by injection into a vein by a health care professional as directed by your doctor, usually at least 15 minutes before a certain blood procedure (plasma exchange). After the first plasma exchange procedure, you should receive another dose given by injection under the skin as directed by your doctor.
After the first day, this medication is given by injection under the skin after each plasma exchange treatment as directed by your doctor, usually once daily for at least 30 days.
If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. If the carton was not stored at room temperature, allow the vial and the syringe to reach room temperature by holding them in your hands for 10 seconds. Do not heat this medication any other way, such as by heating in the microwave or placing in hot water. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Inject this medication under the skin of your abdomen as directed by your doctor.
Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Learn how to store and discard medical supplies safely.
The dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.
Tell your doctor if your condition does not get better or if it gets worse.
Headache, muscle ache, or tiredness may occur. You may bruise or bleed more easily. Nosebleed and bleeding gums may occur. It may take longer than usual to stop bleeding. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any signs of serious bleeding, including: unusual pain/swelling/discomfort, unusually heavy/prolonged menstrual flow, red/dark urine, bloody/black/tarry stools, severe headache, dizziness/fainting, unusual weakness.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before using caplacizumab, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before having surgery or a dental procedure, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication should be temporarily stopped for at least 7 days before having scheduled surgery, dental procedure, or any procedure with increased risk of bleeding.
To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug are: other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen/naproxen, "blood thinners" such as warfarin/dabigatran).
Aspirin can increase the risk of bleeding when used with this medication. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually 81-162 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
If you miss a dose within 12 hours after your scheduled dose, use it as soon as you remember. If it is longer than 12 hours after your scheduled dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
Store in the original carton in the refrigerator away from light. Do not freeze. If needed, this medication may be stored in the original carton at room temperature for up to 2 months. If stored at room temperature, do not put the medication back in the refrigerator. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.