This medication is used to treat a certain blood disorder (acquired thrombotic thrombocytopenic purpura-aTTP). It is used in combination with certain other treatments for this disorder (plasma exchange, immune suppressing medication). In aTTP, blood clots form in small blood vessels throughout the body. These clots can cause serious medical problems if they block vessels and limit or stop blood flow to organs such as the brain, kidneys, and heart. This disorder can also cause red blood cells to break apart faster than the body can replace them, which results in anemia. Caplacizumab-yhdp works by causing your body to make fewer/smaller blood clots.

How to use

Read the Patient Information Leaflet if available from your pharmacist before you start using caplacizumab-yhdp and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

The first dose of this medication is given by injection into a vein by a health care professional as directed by your doctor, usually at least 15 minutes before a certain blood procedure (plasma exchange). After the first plasma exchange procedure, you should receive another dose given by injection under the skin as directed by your doctor.

After the first day, this medication is given by injection under the skin after each plasma exchange treatment as directed by your doctor, usually once daily for at least 30 days.

If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. If the carton was not stored at room temperature, allow the vial and the syringe to reach room temperature by holding them in your hands for 10 seconds. Do not heat this medication any other way, such as by heating in the microwave or placing in hot water. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Inject this medication under the skin of your abdomen as directed by your doctor.

Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Learn how to store and discard medical supplies safely.

The dosage is based on your medical condition and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.

Tell your doctor if your condition does not get better or if it gets worse.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.