Siponimod Oral Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • a high alanine transaminase level
  • a high aspartate transaminase level
  • If experienced, these tend to have a Less Severe expression i

  • pain in the arms or legs
  • dizziness
  • fluid retention in the legs, feet, arms or hands
  • headache
  • diarrhea
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • an infection
  • an atrioventricular conduction defect in the heart
  • seizures
  • accidental falls
  • macular edema
  • prolonged P-R interval observed on EKG
  • a decrease in lung function measurement
  • If experienced, these tend to have a Less Severe expression i

  • a common cold
  • inflammation of the tissue lining the sinuses
  • bronchitis
  • muscle tremors
  • generalized weakness
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • malignant melanoma, a type of skin cancer
  • a cancerous nodule in a testicle called a seminoma
  • a brain infection called cryptococcal meningitis
  • a heart attack
  • a clot in the lung
  • acute thromboembolic stroke
  • meningitis due to varicella zoster virus
  • If experienced, these tend to have a Less Severe expression i

    Sorry, we have no data available. Please contact your doctor or pharmacist.

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.