There may be a slightly increased risk of serious, possibly fatal side effects (such as stroke, heart failure, fast/irregular heartbeat, pneumonia) when this product is used by older adults with dementia. This product is not approved for the treatment of dementia-related behavior problems. Discuss the risks and benefits of this product, as well as other effective and possibly safer treatments for dementia-related behavior problems, with the doctor.


This product is a combination of 2 medications: olanzapine and samidorphan. It is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). This product can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life.Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Samidorphan belongs to a class of drugs known as opioid antagonists. It reduces the risk of weight gain caused by olanzapine.

How to use Olanzapine 15 Mg-Samidorphan 10 Mg Tablet

Read the Medication Guide provided by your pharmacist before you start taking olanzapine/samidorphan and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this product by mouth with or without food as directed by your doctor, usually once daily. Swallow the tablet whole. Do not split the tablet.

The dosage is based on your medical condition and response to treatment. To reduce your risk of side effects, your doctor may direct you to start this product at a low dose and gradually increase your dose. Follow your doctor's instructions carefully.

Take this product regularly to get the most benefit from it. To help you remember, take it at the same time each day. Keep taking this product even if you feel well. Do not stop taking this product without consulting your doctor.

Tell your doctor if your condition does not get better or if it gets worse.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.