This medication is used for the short-term treatment of a breathing problem (apnea) in premature infants. Caffeine blocks certain proteins (adenosine receptors) which lead to improved breathing in these infants.
How to use Caffeine Citrate
Read the Patient Information Leaflet if available from your pharmacist before you start giving this drug and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
This medication is given by mouth or through a feeding tube with or without formula as directed by the doctor, usually once daily. The dosage is based on your infant's weight, medical conditions, and response to therapy. Carefully measure each dose with the provided dosing syringe.
Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.
Because this product does not contain preservatives, discard any unused medicine after preparing the dose for your infant.
Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day.
If your infant's condition lasts or gets worse, tell your doctor or pharmacist.
Nausea, vomiting, stomach upset, headache, trouble sleeping, restlessness, poor feeding, increased urination, rash or dry skin may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: vision changes.
In rare (sometimes, fatal) cases, this medication has been associated with a serious stomach condition (necrotizing enterocolitis). Tell your doctor right away if your infant experiences the following: lack of energy (lethargy), severe vomiting, stomach/abdominal bloating (distension), bloody stool.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Before taking caffeine citrate, tell your doctor or pharmacist if your infant is allergic to it; or if your infant has any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your infant's medical history, especially of: heart disease, kidney disease, liver disease, stomach problems (such as peptic ulcers, necrotizing enterocolitis), seizures.
Infants may be more sensitive to the side effects of this drug, especially the stimulant effects (such as trouble sleeping, restlessness, nervousness).
Older adults may be more sensitive to the side effects of this drug, especially trouble sleeping.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include stomach pain, anxiety, agitation, confusion, irregular or fast heartbeat, frequent urination, muscle twitching, ringing in the ears, trouble sleeping, and seizures.
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.