LEMTRADA Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • anemia
  • decreased blood platelets
  • low levels of a type of white blood cell called neutrophils
  • a decreased number of lymphocytes in the blood
  • abnormal heart rhythm
  • fever
  • wheezing
  • cytokine release syndrome, a sudden activation of the immune system

If experienced, these tend to have a Less Severe expression i

  • throat irritation
  • inflammation of the tissue lining the sinuses
  • bronchitis
  • urinary tract infection
  • itching
  • joint pain
  • dizziness
  • low energy
  • headache
  • nausea
  • vomiting
  • a feeling of pins and needles on skin
  • pain in the oropharynx

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • a bacterial infection
  • shingles
  • an infection due to a virus
  • an infection due to a fungus
  • overactive thyroid gland
  • a condition with low thyroid hormone levels
  • high blood pressure
  • low blood pressure
  • pneumonia
  • the flu
  • a hypersensitivity reaction to a drug

If experienced, these tend to have a Less Severe expression i

  • a herpes simplex infection
  • thrush
  • a yeast infection of the vagina and vulva
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • erythema or redness of skin or mucous membrane
  • difficulty sleeping
  • temporary redness of face and neck
  • decreased appetite
  • diarrhea
  • abnormal sensations of the skin
  • intense abdominal pain
  • anxious feelings

RARE side effects

If experienced, these tend to have a Severe expression i

  • active tuberculosis
  • an infection by the bacteria Listeria monocytogenes
  • infection due to Nocardia bacteria
  • mononucleosis, the kissing disease
  • an unusual viral infection called cytomegalovirus infection
  • a type of systemic fungal infection called coccidioidomycosis
  • a type of fungal lung infection called histoplasmosis
  • a type of systemic fungal infection called aspergillosis
  • sarcoidosis
  • pneumonia with a fungus called Pneumocystis jirovecii
  • malignant melanoma, a type of skin cancer
  • thyroid cancer
  • a goiter
  • thyroid gland inflammation
  • destruction of red blood cells by body's own antibodies
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • low blood counts due to bone marrow failure
  • a decrease in bone marrow production
  • low platelet count and bleeding from immune response
  • increased eosinophils in the blood
  • suicidal behavior
  • suicidal thoughts
  • Guillain-Barre syndrome
  • optic neuropathy, a disease of the optic nerve
  • a heart attack
  • angina, a type of chest pain
  • cardiomyopathy, a disease of the heart muscle
  • atrial fibrillation
  • complete stoppage of the heart
  • sinus bradycardia
  • chronic heart failure
  • abnormal bleeding in the brain resulting in damage to brain tissue, called a hemorrhagic stroke
  • a stroke
  • goodpasture's syndrome
  • thrombotic thrombocytopenic purpura, a type of blood disorder
  • inflammation in the lungs due to an allergic reaction
  • a type of inflammation of the lung called interstitial pneumonitis
  • x-ray results showing lung tissue changes
  • lung failure causing loss of breath
  • acute respiratory distress syndrome, a type of lung disorder
  • bronchospasm
  • liver inflammation resulting from an abnormal immune response
  • glomerulonephritis, a condition that affects the kidneys
  • decreased kidney function
  • rheumatoid arthritis
  • high amount of bilirubin in the blood
  • abnormal liver function tests
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • a serum sickness reaction
  • malignant lymphoma
  • Hashimoto thyroiditis, a disease of the thyroid
  • bleeding from the lungs
  • a condition that results in overproduction of thyroid hormones called Graves' disease
  • Burkitt's lymphoma
  • progressive multifocal leukoencephalopathy, a type of brain infection
  • a nerve disease with muscle weakness called chronic inflammatory demyelinating polyneuropathy
  • acquired hemophilia
  • an increased risk of developing an uncommon viral infection called an opportunistic infection
  • hemophagocytic lymphohistiocytosis, a condition where the body makes too many activated immune cells
  • acute inflammation of the gallbladder
  • bleeding in the alveoli of the lungs
  • a small tear or dissection of the cervicocephalic artery
  • dissection of artery
  • an infection by human papillomavirus
  • Castleman disease
  • tumor lysis syndrome

If experienced, these tend to have a Less Severe expression i

  • large purple or brown skin blotches
  • visual sensitivity to light
  • a change in vision
  • pink eye
  • dry eye
  • fluid accumulation around the eye
  • eye pain
  • ringing in the ears
  • muscle tremors
  • pain in the muscles or bones
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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.