What should I Know Regarding Pregnancy, Nursing and Administering Difenoxin-atropine Oral to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • Not Recommended:

    • If you are nursing

  • Precaution: INSUFFICIENT HUMAN DATA AVAILABLE
  • Precaution: INSUFFICIENT HUMAN DATA AVAILABLE; MAY REDUCE MILK PRODUCTION

    • If you are an adult over 60

  • management or monitoring precaution: Neuro/Psych-Anticholinergic effects may cause sedation, worsen cognitive impairment and increase fall risk. Cardiovascular-May cause orthostatic hypotension at higher doses. Gastrointestinal-May cause or worsen pre-existing constipation. Genitourinary-Best avoided in patients with urinary retention from any cause.
  • management or monitoring precaution: General-May be more susceptible to respiratory depression.

    • Pediatric use

  • Severe Precaution: Safety and efficacy below the age of 12 have not been established.
  • Severe Precaution: Contraindicated in children under 2 years of age. Infants and children are more sensitive to anticholinergic and adverse effects. Adverse CNS effects onset may be sooner and with lower dose.
  • Severe Precaution: Infants and children are more sensitive to anticholinergic and adverse effects. Adverse CNS effects onset may be sooner and with lower dose. Caution in children with spastic paralysis.
    • Full Drug Information

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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.