Does OXYCONTIN Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED OPIOIDS/MIFEPRISTONE
  • OPIOID ANALGESICS/OPIOID ANTAGONISTS
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED OPIOIDS/SELECTED CYP3A4 INHIBITORS
  • CHRONIC OPIOIDS/NALBUPHINE
  • CHRONIC OPIOIDS/BUTORPHANOL
  • CHRONIC OPIOIDS/BUPRENORPHINE
  • SELECTED OPIOIDS/CERITINIB; CRIZOTINIB
  • ANTICHOLINERGICS; OPIOIDS/ELUXADOLINE
  • AGENTS THAT MAY CAUSE RESPIRATORY DEPRESSION/SODIUM OXYBATE
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED OPIOIDS/SELECTED STRONG CYP3A4 INDUCERS
  • SELECTED OPIOID ANALGESICS/CIMETIDINE
  • SELECTED OPIOIDS/SELECTED MODERATE CYP3A4 INHIBITORS
  • SELECTED OPIOIDS/BARBITURATES; PHENOBARBITAL; PRIMIDONE
  • OPIOIDS (EXTENDED RELEASE)/BENZODIAZEPINES
  • OPIOIDS (EXTENDED RELEASE)/SLEEP DRUGS; TRANQUILIZERS
  • OPIOIDS (EXTENDED RELEASE)/MUSCLE RELAXANTS
  • OPIOIDS (EXTENDED RELEASE)/ANTIPSYCHOTICS; PHENOTHIAZINES
  • OXYCODONE/STRONG CYP2D6 INHIBITORS
  • OPIOIDS (EXTENDED RELEASE)/SELECTED STIMULANTS
  • SELECTED OPIOIDS (EXTENDED RELEASE)/METAXALONE
  • AGENTS WITH HYPONATREMIA RISK/DESMOPRESSIN
  • AGENTS WITH HYPONATREMIA RISK/DESMOPRESSIN (NOCTURIA)
  • OPIOIDS (IR & ER)/GABAPENTINOIDS
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.