Does Erythromycin Ethylsuccinate Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED MACROLIDES/SELECTED HMG-COA REDUCTASE INHIBITORS
  • ERYTHROMYCIN/FLUCONAZOLE
  • CYP3A4 SUBSTRATES THAT PROLONG QT/POSACONAZOLE
  • MODERATE CYP3A4 INHIBITORS/LUMATEPERONE (>21 MG)
  • MODERATE CYP3A4 INHIBITORS/MITAPIVAT (> 20 MG)
  • QT PROLONGING AGENTS/LEVOKETOCONAZOLE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LONAFARNIB
  • STRONG CYP3A4 INHIBITORS; ATAZANAVIR;DARUNAVIR/LERCANIDIPINE
  • STRONG & MOD 3A4 INHIB THAT PROLONG QT/CILOSTAZOL (> 50 MG)
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ASUNAPREVIR
  • QT PROLONGING AGENTS/HYDROXYCHLOROQUINE
  • SELECTED QT PROLONGING AGENTS/SAQUINAVIR
  • STRONG OR MODERATE CYP3A4 INHIBITORS/LOMITAPIDE
  • MODERATE CYP3A4 INHIBITORS/NALOXEGOL (> 12.5 MG)
  • QT PROLONGING AGENTS/ANAGRELIDE
  • MODERATE CYP3A4 INHIBITORS/RANOLAZINE (> 500 MG BID)
  • MODERATE CYP3A4 INHIBITORS/AVANAFIL (> 50 MG)
  • STRONG OR MODERATE CYP3A4 INHIBITORS/FLIBANSERIN
  • ERYTHROMYCIN/PITAVASTATIN (>1 MG)
  • SELECTED STRONG CYP3A4 INHIBITORS/DOMPERIDONE; CISAPRIDE
  • ERYTHROMYCIN/LURASIDONE (> 80 MG)
  • QT PROLONGING AGENTS/DRONEDARONE
  • QT PROLONGING AGENTS/DISOPYRAMIDE
  • SELECTED CYP3A4 INHIBITORS/VARDENAFIL (> 5 MG)
  • QT PROLONGING AGENTS/SERTINDOLE
  • QT PROLONGING AGENTS/DROPERIDOL
  • SLT MACRO;KETOLIDE ANTIBIOTICS/ELETRIPTAN
  • QT PROLONGING AGENTS/LEVOMETHADYL
  • QT PROLONGING AGENTS/SPARFLOXACIN
  • QT PROLONGING AGENTS/HALOFANTRINE
  • QT PROLONGING AGENTS/BEPRIDIL
  • SELECTED MACROLIDE ANTIBIOTICS/PIMOZIDE
  • SELECTED AGENTS/MIBEFRADIL
  • SELECTED MACROLIDE ANTIBIOTICS/ERGOT ALKALOIDS
  • ANTIMICROBIALS/LIVE TYPHOID VACCINE
  • ERYTHROMYCIN/GREPAFLOXACIN
  • MACROLIDE ANTIBIOTICS/ASTEMIZOLE; TERFENADINE
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • CLARITHROMYCIN; ERYTHROMYCIN/QUINUPRISTIN-DALFOPRISTIN
  • ERYTHROMYCIN; TELITHROMYCIN/ITRACONAZOLE; KETOCONAZOLE
  • SELECTED MACROLIDES/SELECTED CALCIUM CHANNEL BLOCKERS
  • ERYTHROMYCIN/TROLEANDOMYCIN
  • ERYTHROMYCIN/QT PROLONGING AGENTS
  • ERYTHROMYCIN/LUMACAFTOR-IVACAFTOR
  • SELECTED MACROLIDES/TACROLIMUS
  • MODERATE CYP3A4 INHIBITORS/MAVACAMTEN
  • MODERATE CYP3A4 INHIBITORS THAT PROLONG QT/PACRITINIB
  • MACROLIDE ANTIBIOTICS/ORAL MIDAZOLAM
  • QT PROLONGING AGENTS/PANOBINOSTAT
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/BILASTINE
  • STRONG & MODERATE 3A4 INHIB THAT PROLONG QT/ENCORAFENIB
  • SELECTED QT PROLONGING AGENTS/INTRAVENOUS LEFAMULIN
  • MODERATE 3A4 INHIBITORS THAT PROLONG QT/MOBOCERTINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/DOXORUBICIN
  • STRONG & MODERATE 3A4 INHIBITOR THAT PROLONG QT/FEXINIDAZOLE
  • OATP1B1-3 INHIBITORS/BRINCIDOFOVIR
  • STRONG AND MODERATE CYP3A4 INHIBITORS/INFIGRATINIB
  • SELECTED MODERATE CYP3A4 INHIBITORS/ALPRAZOLAM
  • MODERATE CYP3A4 INHIBITORS/VOCLOSPORIN
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/RELUGOLIX
  • QT PROLONGING AGENTS/LEVOMEPROMAZINE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LURBINECTEDIN
  • MODERATE CYP3A4 INHIBITORS THAT PROLONG QT/SELPERCATINIB
  • MODERATE CYP3A4 INHIBITORS/PEXIDARTINIB
  • MODERATE CYP3A4 INHIBITORS THAT PROLONG QT/IVABRADINE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/PEMIGATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/SELUMETINIB
  • QT PROLONGING AGENTS/OXALIPLATIN
  • P-GP OR BCRP INHIBITORS THAT PROLONG QT/PAZOPANIB
  • MODERATE CYP3A4 INHIBITORS/TAZEMETOSTAT
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LEMBOREXANT
  • MODERATE CYP3A4 INHIBITORS/ELEXACAFTOR-TEZACAFTOR-IVACAFTOR
  • STRONG & MOD CYP3A4 INHIBITOR THAT PROLONG QT/ORAL LEFAMULIN
  • MODERATE CYP3A4 INHIBITORS THAT PROLONG QT/ENTRECTINIB
  • MODERATE CYP3A4 INHIBITORS/BRIGATINIB
  • QT PROLONGING AGENTS/GLASDEGIB
  • CLARITHROMYCIN; ERYTHROMYCIN; VERAPAMIL/RIVAROXABAN
  • QT PROLONGING AGENTS/LOFEXIDINE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/TEZACAFTOR-IVACAFTOR
  • QT PROLONGING AGENTS/MACIMORELIN
  • QT PROLONGING AGENTS/INOTUZUMAB OZOGAMICIN
  • STRONG CYP3A4 INHIB;MODERATE 3A4 & P-GP DUAL INHIB/NERATINIB
  • MODERATE CYP3A4 INHIBITORS THAT PROLONG QT/QUETIAPINE
  • QT PROLONGING AGENTS/RIBOCICLIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/DEFLAZACORT
  • SELECTED ANTIBIOTICS/CHOLERA VACCINE LIVE
  • QT PROLONGING AGENTS/HYDROXYZINE
  • QT PROLONGING AGENTS/PIMAVANSERIN
  • MODERATE CYP3A4 INHIBITORS/VENETOCLAX
  • QT PROLONGING AGENTS/VEMURAFENIB
  • QT PROLONGING AGENTS/TELAVANCIN
  • QT PROLONGING AGENTS/SORAFENIB
  • QT PROLONGING AGENTS/ROMIDEPSIN
  • QT PROLONGING AGENTS/ONDANSETRON
  • QT PROLONGING AGENTS/LENVATINIB
  • QT PROLONGING AGENTS/GADOFOSVESET
  • QT PROLONGING AGENTS/EZOGABINE
  • QT PROLONGING AGENTS/CRIZOTINIB
  • QT PROLONGING AGENTS/CERITINIB
  • QT PROLONGING AGENTS/BEDAQUILINE
  • QT PROLONGING AGENTS/OSIMERTINIB
  • QT PROLONGING AGENTS/DONEPEZIL
  • QT PROLONGING AGENTS/CHLORPROMAZINE
  • QT PROLONGING AGENTS/CHLOROQUINE
  • QT PROLONGING AGENTS/SOTALOL
  • QT PROLONGING AGENTS/PROCAINAMIDE
  • QT PROLONGING AGENTS/IBUTILIDE
  • QT PROLONGING AGENTS/FLECAINIDE
  • OATP1B1 INHIBITORS/ELUXADOLINE
  • SELECTED P-GP INHIBITORS/EDOXABAN (> 30 MG)
  • MODERATE CYP3A4 INHIBITORS/NALOXEGOL (<= 12.5 MG)
  • QT PROLONGING AGENTS/DELAMANID
  • MODERATE CYP3A4 INHIBITORS/COBIMETINIB; OLAPARIB; SONIDEGIB
  • STRONG & MODERATE CYP3A4 INHIBITORS/ELIGLUSTAT
  • MODERATE CYP3A4 INHIBITORS/SUVOREXANT (> 10 MG)
  • QT PROLONGING AGENTS/TRAZODONE (>= 100 MG)
  • STRONG & MODERATE CYP3A4 INHIBITORS/GUANFACINE
  • STRONG OR MODERATE CYP3A4 INHIBITORS/SIMEPREVIR
  • STRONG AND MODERATE CYP3A4 INHIBITORS/BOSENTAN
  • QT PROLONGING AGENTS/DOFETILIDE
  • MODERATE CYP3A4 INHIBITORS/BOSUTINIB
  • SELECTED CYP3A4 INHIBITOR/TOLTERODINE (>1 MG IR OR >2 MG ER)
  • STRONG AND MODERATE CYP3A4 INHIBITORS/IVACAFTOR
  • QT PROLONGING AGENTS/PROPAFENONE
  • QT PROLONGING AGENTS/ILOPERIDONE
  • QT PROLONGING AGENTS/LOPINAVIR
  • QT PROLONGING AGENTS/TOREMIFENE
  • MODERATE CYP3A4 INHIBITORS/COLCHICINE
  • MODERATE CYP3A4 INHIBITORS/TOLVAPTAN
  • AZITHROMYCIN;ERYTHROMYCIN;TROLEANDOMYCIN/QUINIDINE; QUININE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TOPOTECAN
  • QT PROLONGING AGENTS/ZUCLOPENTHIXOL
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/DABIGATRAN
  • QT PROLONGING AGENTS/NILOTINIB
  • QT PROLONGING AGENTS/PALIPERIDONE
  • SELECTED QT PROLONGING AGENTS/ZIPRASIDONE
  • SELECTED CYP3A4 INHIBITORS/SELECTED OPIOIDS
  • QT PROLONGING AGENTS/AMIODARONE
  • SELECTED MODERATE CYP3A4 INHIBITORS/EPLERENONE
  • CLARITHROMYCIN; ERYTHROMYCIN; TELITHROMYCIN/RIFAMYCINS
  • SELECTED MACROLIDES/SELECTED IMMUNOSUPPRESSANTS;TEMSIROLIMUS
  • MACROLIDE ANTIBIOTICS/DIGOXIN, ORAL
  • MACROLIDE ANTIBIOTICS/CARBAMAZEPINE
  • SLT MACROLIDE ANTIBIOTICS/SLT ANTICOAGULANTS (VIT K ANTAG)
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • ERYTHROMYCIN/RIFABUTIN
  • ERYTHROMYCIN/POSSIBLE QT PROLONGING AGENTS
  • CLARITHROMYCIN; ERYTHROMYCIN/SELECTED STRONG CYP3A4 INDUCERS
  • ERYTHROMYCIN/NIRMATRELVIR-RITONAVIR
  • MODERATE CYP3A4 INHIBITORS/LUMATEPERONE (<=21 MG)
  • QT PROLONGING AGENTS/TRICLABENDAZOLE
  • MODERATE CYP3A4 INHIBITORS/MITAPIVAT (<= 20 MG)
  • MODERATE CYP3A4 INHIBITORS/DARIDOREXANT
  • SLT MODERATE AND WEAK CYP3A4 INHIBIT/SIROLIMUS PROTEIN-BOUND
  • OATP1B1-3 INHIBITORS/ATOGEPANT
  • QT PROLONGING AGENTS/OZANIMOD
  • QT PROLONGING AGENTS/PONESIMOD
  • QT PROLONGING AGENTS/SIPONIMOD
  • QT PROLONGING AGENTS/GALANTAMINE
  • MODERATE CYP3A4 INHIBITORS THAT PROLONG QT/IVOSIDENIB
  • QT PROLONGING AGENTS/OSILODROSTAT
  • QT PROLONGING AGENTS/AMISULPRIDE
  • MODERATE CYP3A4 INHIBITORS/RIMEGEPANT
  • MODERATE CYP3A4 INHIBITORS/AVAPRITINIB
  • MODERATE CYP3A4 INHIBITORS/UBROGEPANT
  • MODERATE CYP3A4 INHIBITORS/ZANUBRUTINIB
  • ERYTHROMYCIN; FLUCONAZOLE; ROXITHROMYCIN/TRIAZOLAM
  • QT PROLONGING AGENTS/PITOLISANT
  • QT PROLONGING AGENTS/GILTERITINIB
  • MODERATE CYP3A4 INHIBITORS/ABEMACICLIB
  • SELECTED P-GP INHIBITORS/EDOXABAN (<= 30 MG)
  • QT PROLONGING AGENTS/TRAZODONE (< 100 MG)
  • SELECTED MODERATE CYP3A4 INHIBITORS/ACALABRUTINIB
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/BETRIXABAN
  • QT PROLONGING AGENTS/EFAVIRENZ
  • SELECTED MACROLIDE ANTIBIOTICS/BROMOCRIPTINE; CABERGOLINE
  • QT PROLONGING AGENTS/ERIBULIN
  • MODERATE CYP3A4 INHIBITORS/BREXPIPRAZOLE
  • P-GP AND MODERATE CYP3A4 INHIBITORS/APIXABAN
  • P-GP AND SELECTED CYP3A4 INHIBITORS/NINTEDANIB
  • MODERATE CYP3A4 INHIBITORS/SUVOREXANT (<= 10 MG)
  • MODERATE CYP3A4 INHIBITORS/IBRUTINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
  • QT PROLONGING AGENTS/ALFUZOSIN
  • QT PROLONGING AGENTS/FINGOLIMOD
  • QT PROLONGING AGENTS/VORICONAZOLE
  • SELECTED CYP3A4 INHIBITORS/VARDENAFIL (<= 5 MG)
  • ERYTHROMYCIN/LURASIDONE (<= 80 MG)
  • ERYTHROMYCIN/ATORVASTATIN; PITAVASTATIN (<=1MG); PRAVASTATIN
  • MODERATE CYP3A4; P-GP INHIBITORS/EVEROLIMUS
  • MODERATE CYP3A4 INHIBITORS/RANOLAZINE (<=500 MG BID)
  • CYP3A4; CYP2C8; P-GLYCOPROTEIN (P-GP) INHIBITORS/LOPERAMIDE
  • STRONG CYP3A4 INHIBITORS/BUSPIRONE
  • ERYTHROMYCIN/ESZOPICLONE; ZOPICLONE
  • SELECTED CYP3A4 INHIBITORS/TOLTERODINE (<=1 MG OR <=2 MG ER)
  • MACROLIDE ANTIBIOTICS/MIDAZOLAM
  • STRONG & MOD 3A4 INHIB THAT PROLONG QT/CILOSTAZOL (<=50MG)
  • SELECTED MACROLIDE ANTIBIOTICS/CORTICOSTEROIDS
  • SELECTED MACROLIDE ANTIBIOTICS/SELECTED XANTHINE DERIVATIVES
  • Free RX Coupon

    Save up to 80% on your prescriptions.

    Available coupons

    Save up to 80% on your prescription with WebMDRx

    Drug Survey

    Are you currently using Erythromycin Ethylsuccinate?

    This survey is being conducted by the WebMD marketing sciences department.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.