What should I Know Regarding Pregnancy, Nursing and Administering Dolophine Injection to Children or the Elderly?

If you are pregnant

  • Not Recommended:

    • If you are nursing

  • Precaution: BREASTFEEDING ACCEPTABLE DURING TREATMENT; MONITOR INFANT FOR RESP DEPRESSION

    • If you are an adult over 60

  • management or monitoring precaution: Pulmonary-DO NOT use in opioid intolerance. Increased risk of fatal respiratory depression due to altered pharmacokinetics. Monitor closely at initiation and dose titration and when giving with other drugs that cause respiratory depression. Consider naloxone Rx. Renal-Start with low dose for renal impairment. Neuro/Psych-Risk for confusion, delirium and falls. Avoid treatment with 3 or more CNS active agents. Cardiovascular-QT prolongation risk; syncope risk.

    • Pediatric use

  • Severe Precaution: Potential increased sensitivity to effects, adverse CNS effects and respiratory depression. Safety, effectiveness, and pharmacokinetics not established in pediatric patients. With any opioid, access to naloxone for emergency reversal can mitigate risk from accidental ingestion/overdose.
  • Severe Precaution: Safety, effectiveness, and pharmacokinetics not established in age < 18 years. With any opioid, access to naloxone for emergency reversal can mitigate risk from accidental ingestion/overdose.
    • Full Drug Information

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.