What should I Know Regarding Pregnancy, Nursing and Administering Guaifenesin/P-Ephedrine/Cod Oral to Children or the Elderly?
If you are pregnant
Not Recommended: Not Recommended: Not Recommended: If you are nursing
Precaution: RESP DEP POSS IN INFANT,NON-OPIOID ALT REC, OR USE LOW DOSE SHORTEST DURATION Precaution: MAY DECREASE MILK SUPPLY AND CAUSE IRRITABILITY Precaution: INSUFFICIENT HUMAN DATA AVAILABLE If you are an adult over 60
management or monitoring precaution: General-Consider adding naloxone Rx. Pulmonary-Life threatening respiratory depression risk with high doses, cachexia, or debilitation due to altered pharmacokinetics (poor fat stores, muscle wasting, or altered clearance). Monitor closely at initiation and dose titration. Neuro/Psych-Risk for increased confusion and delirium. May increase fall risk. Avoid treatment with 3 or more CNS active drugs. Gastrointestinal-Constipation risk. Urogenital-Urinary retention risk. management or monitoring precaution: Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk. Pediatric use
Severe Precaution: No established efficacy for cough and cold products age < 2 years. Do not use unless directed by clinician consultation. Severe Precaution: Not indicated for symptoms of cough and cold in pediatrics. Risk of slowed or difficult breathing and respiratory depression. Death reported in CYP2D6 ultra-rapid metabolizers post tonsillectomy or adenoidectomy. Severe Precaution: High risk of adverse CNS effects. Not recommended for use age < 6 years. Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
