What should I Know Regarding Pregnancy, Nursing and Administering Divalproex SODIUM to Children or the Elderly?
If you are PREGNANT
- Absolute Contraindication: FDA X FOR MIGRAINE PROPHYLAXIS, FDA D FOR EPILEPSY AND MANIA
If you are NURSING
- Precaution: ONE CASE OF THROMBOCYTOPENIA REPORTED, MONITOR INFANT FOR ADVERSE EFFECTS
If you are an adult over 60
- management or monitoring precaution: Hepatic-Elderly may have slower metabolism and protein binding which requires dosage reduction. Monitor closely. Neuro/Psych-Use caution in elderly with a history of recurrent falls. Drug may produce somnolence, ataxia, impaired psychomotor function, syncope, and additional falls. Monitor fluid and nutritional intake and avoid dehydration. Musculoskeletal-Postmarketing reports of fractures, decreased bone mineral density, osteopenia, osteoporosis.
Giving Divalproex SODIUM to a child under 12
- Severe Precaution: Increased risk of serious or fatal hepatotoxicity.