Amantadine

Side Effects

Blurred vision, nausea, stomach upset, drowsiness, dizziness, headache, dry mouth, constipation, nervousness, or trouble sleeping may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: purplish-red blotchy spots on the skin, swelling of the ankles/feet, difficulty urinating, vision changes.

Tell your doctor right away if any of these rare but very serious side effects occur: shortness of breath, mental/mood changes (such as depression, suicidal thoughts/attempts), muscle stiffness, uncontrolled muscle movements, unusual sweating, fast heartbeat, unexplained fever, unusual strong urges (such as increased gambling, increased sexual urges), seizures.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Some people taking amantadine have fallen asleep suddenly during their usual daily activities (such as talking on the phone, driving). In some cases, sleep occurred without any feelings of drowsiness beforehand. This sleep effect may occur anytime during treatment with amantadine even if you have used this medication for a long time. If you experience increased sleepiness or fall asleep during the day, do not drive or take part in other possibly dangerous activities until you have discussed this effect with your doctor. Your risk of this sleep effect is increased by using alcohol or other medications that can make you drowsy. See also Precautions section.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Before taking amantadine, tell your doctor or pharmacist if you are allergic to it; or to rimantadine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain type of eye disease (untreated closed-angle glaucoma).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: swelling of arms/legs (peripheral edema), heart problems (e.g., congestive heart failure), blood pressure problems (e.g., dizziness when standing), kidney disease, liver disease, mental/mood conditions (e.g., depression, psychosis), seizures, a certain skin condition (eczematoid dermatitis).

This drug may make you dizzy or drowsy or blur your vision. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). See also Side Effects section.

To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.

If you are taking this medication for Parkinson's disease, be careful not to overdo physical activity as your condition improves because this may increase your risk of falls. Consult your doctor about a plan to gradually increase your physical activity as symptoms improve.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at a greater risk for side effects while taking this drug.

This medication should be used during pregnancy only if clearly needed. There are rare reports of heart defects in newborns whose mothers took amantadine during pregnancy. Discuss the risks and benefits with your doctor.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult with your doctor before breast-feeding.

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Amantadine may interfere with the effect of certain vaccines, such as flu vaccine inhaled through the nose. However, you may get a flu shot (flu vaccine given by injection) if recommended by your doctor.

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include fast/irregular heartbeats, severe drowsiness, shortness of breath, change in the amount of urine, mental/mood changes (e.g., anxiety, aggression, confusion, hallucinations), seizures.

Notes

Do not share this product with others.

People with Parkinson's disease may have an increased risk for developing skin cancer (melanoma). If you are taking this drug to treat Parkinson's disease, tell your doctor promptly if you notice a change in the appearance or size of moles or other unusual skin changes. Ask your doctor if you should have regular skin exams.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised October 2018. Copyright(c) 2018 First Databank, Inc.