What should I Know Regarding Pregnancy, Nursing and Administering CISPLATIN to Children or the Elderly?

If you are PREGNANT

  • Not Recommended:

If you are NURSING


If you are an adult over 60

  • management or monitoring precaution: General-Increased risk for adverse effects (e.g. renal, neuro, myelosuppression, infection). Renal-Increased susceptibility to nephrotoxicity; may consider reduced dose. Contraindicated with pre-existing renal impairment. Neuro/Psych-Increased risk of peripheral neuropathy in elderly. Endocrine-May exacerbate or cause hyponatremia; monitor sodium level closely when starting or changing dosages. Rare risk of SIADH.

Giving Haloperidol to a child under 12

  • Severe Precaution: Severe ototoxicity and vestibular toxicity observed. Risk may increase with thiopurine S-methyltransferase gene variant. Audiometry recommended prior to, during and after treatment. No safety and efficacy established.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.