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    Cisplatin Vial


    What should I know regarding pregnancy, nursing and administering Cisplatin Vial to children or the elderly?

    If you are:


    Not Recommended:


    Absolute Contraindication: MANUFACTURER DOES NOT RECOMMEND

    An adult over 60:

    management or monitoring precaution: General-Increased risk for adverse effects (e.g. renal, neuro, hematologic). Urogenital-Increased susceptibility to nephrotoxicity; may consider reduced dose. Neuro/Psych-Increased risk of peripheral neuropathy in elderly. Endocrine-May exacerbate or cause SIADH and hyponatremia; monitor sodium level closely when starting or changing dosages.

    Giving cisplatin Vial to a child under 12:

    Severe Precaution: Severe ototoxicity and vestibular toxicity observed. Risk may increase with thiopurine S-methyltransferase gene variant. Audiometry recommended prior to, during and after treatment. No safety and efficacy established.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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