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    Ethionamide Tablet

    COMMON BRAND NAME(S): Trecator

    GENERIC NAME(S): Ethionamide

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    Uses

    Ethionamide is used with other medications to treat tuberculosis (TB). Ethionamide is an antibiotic and works by stopping the growth of bacteria.

    This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

    How to use Ethionamide Tablet

    Take this medication by mouth with or without food, usually once daily or as directed by your doctor. If this medication causes stomach upset or nausea/vomiting, take this medication with meals. Also, discuss with your doctor if it may be helpful to divide your daily dose into smaller doses to be taken several times a day. Follow your doctor's instructions carefully.

    The dosage is based on your age, weight, medical condition, and response to treatment.

    For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same time(s) every day.

    Continue to take this medication (and other TB medications) until the full prescribed amount is finished, even if symptoms disappear. Stopping the medication too early or skipping doses may allow the bacteria to continue to grow, which may result in a return of the infection and cause the infection to be more difficult to treat (resistant).

    Your doctor may also direct you to take vitamin B6 (pyridoxine) to help prevent certain side effects (such as nerve problems) from ethionamide. Follow your doctor's instructions carefully.

    Tell your doctor if your condition persists or worsens.

    Side Effects

    Nausea, vomiting, diarrhea, abdominal/stomach pain, increased saliva, strange metallic taste in the mouth, loss of appetite, or sores in the mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

    Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication may develop serious side effects, but with frequent visits to your doctor, this risk can be minimized.

    Tell your doctor right away if any of these unlikely but serious side effects occur: unusual hunger, unusual sweating, shakiness, persistent nausea/vomiting, unusual tiredness/weakness, yellowing eyes/skin, dark urine, joint pain/swelling, slow heartbeat, mental/mood changes (such as nervousness, restlessness, depression).

    Tell your doctor right away if any of these rare but seriousvision changes (such as blurred/decreased/double vision, color blindness), eye pain, numbness/tingling of arms/legs.

    A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

    This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

    In the US -

    Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

    In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

    Precautions

    Before taking ethionamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

    Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, underactive thyroid (hypothyroidism), eye problems (such as optic neuritis, cataracts, diabetic retinopathy).

    Alcohol may increase the risk of liver disease or mental/mood changes. Avoid alcoholic beverages while using this medication.

    Ethionamide may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.

    Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

    If you have diabetes, this product may lower your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of low blood sugar, such as sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

    This medication is not recommended for use during pregnancy. It may harm an unborn baby. Consult your doctor for more details.

    It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

    Interactions

    The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

    To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

    Keep a list of all the products you use. Share the list with your doctor and pharmacist to reduce your risk for serious medication problems.

    Overdose

    If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

    Notes

    Do not share this medication with others.

    Laboratory and/or medical tests (such as sputum test, eye/vision exams, liver/thyroid function, blood glucose, complete blood count) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

    Missed Dose

    For the best possible benefit, it is important to take each scheduled dose of this medication as directed. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

    Storage

    Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

    Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised February 2017. Copyright(c) 2017 First Databank, Inc.

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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