COMMON side effects

If experienced, these tend to have a Severe expression i

• an infection
• a skin rash
• trouble breathing

If experienced, these tend to have a Less Severe expression i

• dry skin
• low energy
• decreased appetite
• cough
• nausea
• vomiting
• diarrhea

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

• pink eye
• stomatitis, a condition with painful swelling and sores inside the mouth
• keratoconjunctivitis sicca, or dry and inflamed cornea and conjunctiva of the eye

If experienced, these tend to have a Less Severe expression i

• an increased number of eyelashes
• itching
• joint pain
• muscle pain

RARE side effects

If experienced, these tend to have a Severe expression i

• decreased blood platelets
• a disease with shrinking and weaker muscles called myopathy
• inflammation of the uvea of the eye
• an ulcer of the cornea of the eye
• a heart attack
• a stroke
• thrombotic thrombocytopenic purpura, a type of blood disorder
• x-ray results showing lung tissue changes
• inflammation of the large intestine
• liver failure
• acute renal failure in patients with serious liver disease
• bleeding of the stomach or intestines
• acute kidney failure
• decreased kidney function
• inflammation of the skin with blisters
• a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
• a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
• skin rash with sloughing
• a condition with muscle tissue breakdown called rhabdomyolysis
• high amount of bilirubin in the blood
• abnormal liver function tests
• a rupture in the wall of the stomach or intestine
• lung tissue problem
• a hole developing in the cornea of the eye

If experienced, these tend to have a Less Severe expression i

• a nail disorder
• hirsutism, a condition of hair growth on parts of the body normally without hair
• darkening of the skin