LENALIDOMIDE Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • anemia
  • decreased blood platelets
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • trouble breathing
  • If experienced, these tend to have a Less Severe expression i

  • throat irritation
  • constipation
  • itching
  • dry skin
  • joint pain
  • backache
  • dizziness
  • low energy
  • muscle tremors
  • numbness
  • weight loss
  • headache
  • cough
  • nausea
  • diarrhea
  • generalized weakness
  • intense abdominal pain
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • an infection
  • squamous cell carcinoma
  • low amount of phosphate in the blood
  • low amount of calcium in the blood
  • dehydration
  • low amount of potassium in the blood
  • a decreased number of lymphocytes in the blood
  • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
  • atrial fibrillation
  • obstruction of a blood vessel by a blood clot
  • blood clot in a deep vein of the extremities
  • pneumonia
  • bronchitis
  • visible water retention
  • chest pain
  • If experienced, these tend to have a Less Severe expression i

  • a stuffy and runny nose
  • inflammation of the tissue lining the sinuses
  • dry mouth
  • muscle weakness
  • pain in the arms or legs
  • difficulty sleeping
  • excessive sweating
  • chills
  • taste impairment
  • decreased appetite
  • vomiting
  • loose stools
  • high blood sugar
  • bruising
  • a feeling of pins and needles on skin
  • chest pains unrelated to heart problems
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • diarrhea from an infection with Clostridium difficile bacteria
  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • shingles
  • a type of cancer of the lymph nodes called Hodgkin's lymphoma
  • acute myeloid leukemia, a type of blood cancer
  • a condition with low thyroid hormone levels
  • diabetes
  • low amount of magnesium in the blood
  • destruction of red blood cells by body's own antibodies
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • increased eosinophils in the blood
  • mental problems from taking the drug
  • encephalitis
  • fluid accumulation in the brain
  • a sudden loss of vision
  • vision loss
  • high blood pressure
  • a heart attack
  • a clot in the lung
  • supraventricular tachycardia
  • atrial flutter
  • heart failure
  • acute cerebral infarction
  • a stroke
  • cerebral ischemia, a lack of blood supply to the brain
  • a localized weakening and ballooning in an artery wall called an arterial aneurysm
  • thrombophlebitis, an inflamed vein due to a blood clot
  • a blood clot
  • orthostatic hypotension, a form of low blood pressure
  • low blood pressure
  • bleeding
  • inflammation in the lungs due to an allergic reaction
  • fluid in the lungs
  • a type of stomach irritation called gastritis
  • acute liver failure
  • inflammation of the liver called hepatitis
  • bleeding of the stomach or intestines
  • renal tubular necrosis, a kidney disorder
  • kidney failure
  • decreased kidney function
  • bloody urine
  • inflammation of the skin with blisters
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • skin rash with sloughing
  • Sweet's disease
  • abnormal peeling of skin
  • a condition with muscle tissue breakdown called rhabdomyolysis
  • myelodysplastic syndrome, a bone marrow disorder
  • delirium
  • mental status changes
  • swollen lymph nodes
  • an inability to completely empty the bladder
  • bacteria in the blood
  • abnormal liver function tests
  • decreased oxygen in the tissues or blood
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • rejection of a transplanted organ
  • inflammation of the liver with stoppage of bile flow
  • inflammation of a vein
  • reactivation of hepatitis B infection
  • pancreatitis
  • progressive multifocal leukoencephalopathy, a type of brain infection
  • lymphedema, or swelling due to blockage of lymph nodes
  • a type of blood cancer called B-cell acute lymphoblastic leukemia
  • a type of significant allergic skin reaction called DRESS syndrome
  • a high alanine transaminase level
  • tumor lysis syndrome
  • If experienced, these tend to have a Less Severe expression i

  • mood changes
  • altered interest in having sexual intercourse
  • Raynaud's phenomenon, a condition where blood vessels constrict too much with coldness or stress
  • enlarged superficial veins
  • a sore tongue
  • the inability to have an erection
  • hirsutism, a condition of hair growth on parts of the body normally without hair
  • darkening of the skin
  • drowsiness
  • hallucinations
  • abnormal manner of walking
  • loss of muscle coordination
  • loss of skin color
  • temporary redness of face and neck
  • small reddish-purplish pin-point sized spots on skin
  • hoarseness
  • heart throbbing or pounding
  • a feeling of general discomfort called malaise
  • night sweats
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.