First, simple self-care may be enough to relieve most discomfort caused by genital herpes. Taking an over-the-counter pain reliever, such as aspirin, acetaminophen, or ibuprofen, can help ease the pain of herpes symptoms. Doctors sometimes recommend soaking the affected area in warm water. But the area should be kept dry most of the time. If toweling off after bathing is uncomfortable, try using a hair dryer on the "cool" setting. Then put on cotton underwear. Cotton absorbs moisture better than synthetic fabric.