The Gender Gap: How RA Differs in Women

Medically Reviewed by David Zelman, MD on November 02, 2022
2 min read

It isn’t your imagination. If you notice that more of your women friends have rheumatoid arthritis than the guys you know, the stats back it up. About 1.5 million Americans have RA -- and about three times more women have it than men.

The disease acts differently in each gender, too. The more you know, the better you can manage it.

Rheumatoid arthritis tends to strike women at a younger age than men -- and can hit harder, too. In one study, researchers found that women with RA reported more symptoms and more severe ones. Women in the study also didn't do as well when taking the same treatment as men.

Early in the disease, women with RA are also less likely than men to reach "remission," which means they have no symptoms.

Doctors aren’t sure what role sex hormones play in RA. Some women get the disease at times when their sex hormones are shifting, such as after pregnancy or before menopause. If you're pregnant, your RA may improve, but it might flare again after you have your baby. All of this suggests a link to hormones.

If you're breastfeeding, you're less likely to get rheumatoid arthritis. One study shows that women who breastfed for 2 years or more cut their risk of getting the disease in half.

For anyone with RA, man or woman, the key is to start treatment as early as possible. It can halt or slow the disease and prevent joint damage and complications like osteoporosis and heart disease.

There's more to treatment than just medicine. It also helps if you:

  • Stay at a healthy weight
  • Get plenty of sleep
  • Make exercise a habit
  • Rest when you need to
  • Eat healthy foods

And don't forget to ask for help and support when you get tired. Let your friends and family know how you feel and what you need from them.

Show Sources


Karlson, E. Arthritis and Rheumatism, November 2004.

Arthritis Research and Therapy: "Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study."

American College of Rheumatology: "Rheumatoid Arthritis."

Arthritis Foundation: "Arthritis in Women."

Musculoskeletal Report: "Rheumatoid Arthritis Hits Women Harder."

Alpha Galileo: Rheumatoid Arthritis: "Gender differences in experience of rheumatism."

Arthritis Today: "Men Appear More Likely to Achieve Remission in Early RA."

CDC: "Arthritis-Related Statistics."

The Journal of Rheumatology: “Onset of symptoms of rheumatoid arthritis in relation to age, sex and menopausal transition.”

View privacy policy, copyright and trust info