Toxic shock syndrome is rare. It may bring to mind cases linked to tampons, but skin wounds (including from surgery) can also let in the bacteria that cause it. It might give you a rash like sunburn, mainly on your palms or the soles of your feet. It can also cause a fever, low blood pressure, vomiting, diarrhea, confusion, headaches, and red eyes, mouth, and throat. Antibiotics are the main treatment, but you may need other medicine.