Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Mononucleosis (Mono)

Font Size

What Happens

Usually mono is a mild illness that goes away without treatment after several weeks. When you have mono, your symptoms may come and go, and your symptoms may change with time.1

  • A sore throat is worst during the first 3 to 5 days and gradually improves over the next 7 to 10 days.
  • Fever may last 10 to 14 days. Usually it is mild during the last 5 to 7 days. If you have a fever, you should stay home from work or school until the fever goes away. You can then go back to your normal activities if you feel up to it.
  • Swollen lymph nodes camera.gif (sometimes called swollen glands) may last up to 4 weeks.
  • It may take several weeks (even months) for your energy level to return to normal. Don't try to rush this process. Pushing yourself too hard could make you feel worse. Give your body the rest it needs.

Mono can cause your spleen camera.gif to enlarge, making it prone to injury. To reduce the risk of injuring your spleen, avoid heavy lifting and contact sports for several weeks after you become ill with mono (or until a doctor tells you it is okay).

If you know you have mono, you should not donate blood. Epstein-Barr virus (EBV) can be spread through blood products, although this is not common.

Complications of mono are rare but are most likely to develop in very young children, older adults who are in poor health, and people who have impaired immune systems.

In the past, both infectious mononucleosis and chronic fatigue syndrome were thought to be caused by the Epstein-Barr virus. But it is now believed that even though both conditions have some similar symptoms, they are different diseases and chronic fatigue syndrome is not caused by the Epstein-Barr virus.


WebMD Medical Reference from Healthwise

Last Updated: November 14, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Next Article:

Hot Topics

WebMD Video: Now Playing

Click here to wach video: Dirty Truth About Hand Washing

Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

Click here to watch video: Dirty Truth About Hand Washing

Popular Slideshows & Tools on WebMD

disciplining a boy
Types, symptoms, causes.
Remember your finger
Are You Getting More Forgetful?
fruit drinks
Eat these to think better.
No gym workout
Moves to help control blood sugar.
acupuncture needle on shoulder
10 tips to look and feel good.
Close up of eye
12 reasons you're distracted.
birth control pills
Which kind is right for you?
embarrassed woman
Do you feel guilty after eating?
Epinephrine Injection using Auto-Injector Syringe
Life-threatening triggers.
woman biting a big ice cube
Habits that wreck your teeth.
pacemaker next to xray
Treatment options.
caregiver with parent
10 tips for daily life.

Women's Health Newsletter

Find out what women really need.