Skip to content

Information and Resources

Nephrotic Syndrome

Font Size
A
A
A

Nephrotic syndrome is a condition marked by very high levels of protein in the urine; low levels of protein in the blood; swelling, especially around the eyes, feet, and hands; and high cholesterol. Nephrotic syndrome results from damage to the kidneys' glomeruli (the singular form is glomerulus). Glomeruli are tiny blood vessels that filter waste and excess water from the blood and send them to the bladder as urine.

Nephrotic syndrome can occur with many diseases, including the kidney diseases caused by diabetes mellitus, but some causes are unknown. Prevention of nephrotic syndrome relies on controlling these diseases.

Recommended Related to

Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) causes a lot of fluid-filled sacs, called cysts, to grow in your kidneys. The cysts keep your kidneys from working like they should. That can cause health problems like high blood pressure, infections, and kidney stones. It can also cause kidney failure, although that doesn't happen to everyone. You can have ADPKD and not know it for many years. It’s often called “adult PKD,” because the symptoms don't usually appear until people reach ages 30...

Read the Autosomal Dominant Polycystic Kidney Disease article > >

Treatment of nephrotic syndrome focuses on identifying the underlying cause if possible and reducing high cholesterol, blood pressure, and protein in urine through diet, medications, or both. One group of blood pressure medications called ACE inhibitors also protects the kidneys in diabetic patients.

Nephrotic syndrome may go away once the underlying cause, if known, has been treated. However, most of the time a kidney disease is the underlying cause, and these diseases cannot be cured. In these cases, the kidneys may gradually lose their ability to filter wastes and excess water from the blood. If kidney failure occurs, the patient will need dialysis or a kidney transplant.

For More Information

American Kidney Fund
6110 Executive Boulevard
Rockville, MD 20852
(800) 638-8299

National Heart, Lung, and Blood Institute
Information Center
P.O. Box 30105
Bethesda, MD 20824-0105
nhlbiic@dgysys.com
(301) 251-1222

National Kidney Foundation
30 East 33rd Street
New York, NY 10016
(800) 622-9010

Additional Information on Nephrotic Syndrome

The National Kidney and Urologic Diseases Information Clearinghouse collects resource information on kidney and urologic diseases for the Combined Health Information Database (CHID). CHID is a database produced by health-related agencies of the Federal Government. This database provides titles, abstracts, and availability information for health information and health education resources.

To provide you with the most up-to-date resources, information specialists at the clearinghouse created an automatic search of CHID. Or, if you wish to perform your own search of the database, you may access the CHID Online web site (http://chid.nih.gov) and search CHID yourself.

WebMD Public Information from the U.S. National Institutes of Health

Hot Topics

WebMD Video: Now Playing

Click here to wach video: Dirty Truth About Hand Washing

Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

Click here to watch video: Dirty Truth About Hand Washing

Popular Slideshows & Tools on WebMD

feet
Solutions for 19 types.
MS Overview
Recognizing symptoms.
pregnancy test and calendar
Helping you get pregnant.
build a better butt
How to build a better butt.
lone star tick
How to identify that bite.
woman standing behind curtains
How it affects you.
brain scan with soda
Tips to avoid complications.
row of colored highlighter pens
Tips for living better.
psoriasis
How to keep flares at bay.
woman dreaming
What Do Your Dreams Say About You?
spinal compression fracture
Treatment options.

Pollen counts, treatment tips, and more.

It's nothing to sneeze at.

Loading ...

Sending your email...

This feature is temporarily unavailable. Please try again later.

Thanks!

Now check your email account on your mobile phone to download your new app.

Women's Health Newsletter

Find out what women really need.