Nephrotic syndrome is a condition marked by very high levels of protein in the urine; low levels of protein in the blood; swelling, especially around the eyes, feet, and hands; and high cholesterol. Nephrotic syndrome results from damage to the kidneys' glomeruli (the singular form is glomerulus). Glomeruli are a network of capilaries that filter waste and excess water from the blood and send them to the bladder as urine.
Nephrotic syndrome can occur with many diseases, including the kidney diseases caused by diabetes mellitus, but some causes are unknown. Treatment of nephrotic syndrome relies on controlling these diseases.
It is possible that the main title of the report Nephrogenic Systemic Fibrosis is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Nephrotic syndrome may go away once the underlying cause, if known, has been treated. However, most of the time a kidney disease is the underlying cause. Sometimes the type of disease is obvious, such as diabetes, but often a kidney biopsy is required. Depending on the disease, a cure may or may not be possible. In cases where the disease cannot be halted or reversed, the kidneys may gradually lose their ability to filter wastes and excess water from the blood. If kidney failure occurs, the patient will need dialysis or a kidney transplant.
For More Information
American Kidney Fund 6110 Executive Boulevard
Rockville, MD 20852
National Heart, Lung, and Blood Institute Information Center
P.O. Box 30105
Bethesda, MD 20824-0105
National Kidney Foundation 30 East 33rd Street
New York, NY 10016
Additional Information on Nephrotic Syndrome
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To provide you with the most up-to-date resources, information specialists at the clearinghouse created an automatic search of CHID. Or, if you wish to perform your own search of the database, you may access the CHID Online web site (http://chid.nih.gov) and search CHID yourself.
WebMD Public Information from the U.S. National Institutes of Health
"The National Institute of Diabetes and Digestive and Kidney Diseases of The National Institutes of Health. Nephrotic Syndrome. NIH Publication No. 99-4624. February 3, 1998. (Online) http://www.niddk.nih.gov/health/kidney/summary/nephsynd/nephsynd.htm"