Long-term (chronic) stress is the type of stress that causes the most serious problems. It is caused by a host of irritating hassles over a period of time, or an ongoing, difficult situation. Conditions that may lead to chronic stress include:

• Health problems, if you have a chronic illness such as heart disease, diabetes or arthritis.
• Emotional problems, such as unexpressed or uncontrolled anger, depression, grief, guilt, or low self-esteem.
• Relationship problems, if you do not have someone to share your feelings with, are having difficulty in a relationship, or feel that you have few friends.
• Your surroundings, if you live in a dangerous or uncomfortable area where overcrowding, crime, pollution, or noise is a problem.
• Your job, if you are unhappy with your work, or your work is dangerous or too demanding. For more information, see the topic Managing Job Stress.
• Your social situation, such as poverty, loneliness, or discrimination based on race, gender, age, or sexual orientation.
• Life cycle transitions and developmental stages, such as becoming a teenager, leaving home, or getting married.
• Conflicts with your belief system-your perceptions and beliefs about the world, life, and yourself. For instance, if you place a high value on family life but don't have the family life you want, you may feel stress.
• A child or teen, or other family member who is under stress because of physical or emotional problems.