'Rarely the First Clue' continued...
In addition, Laine, who is senior deputy editor of the Annals of Internal Medicine, notes that certain illnesses may cause nail changes in some patients but not in others. "For example, not all people with liver disease develop white nails," Laine tells WebMD. The reverse is true as well -- not everyone with white nails has liver disease. "In the absence of other signs or symptoms of disease, I would be reluctant to launch a complex, expensive work-up for systemic disease solely because of nail findings."
Fox agrees there is no need to run to the nearest cardiologist if your nail beds turn red. "It could very well be from nail polish," he says. Before assuming the worst, it's important to look at more common explanations, such as bruises, bleeding beneath the nail, and fungal infections. However, it's worthwhile to be vigilant about maintaining healthy fingernails so that you'll be alert to any potential problem.
When to See a Dermatologist
When healthy fingernails begin to change color or texture, one of the most common underlying causes is fingernail fungus, which can cause the nails to crack, peel, and change color and texture. These infections often prove difficult to treat and may require professional help, including prescription antifungal medications. Fox says it's best to see a dermatologist if symptoms persist, especially if the nails start to dislodge from the base or you experience pain and swelling.
Be alert to changes in texture, shape, or color that aren't due to a bruise or fungal infection, including irregular growth, pitting or holes in the nails, dark brown streaks beneath the nail and cuticle, or long-standing warts on the nail bed. Any such color change to previously healthy fingernails is cause for concern. According to Lior, such changes can indicate skin cancer. "Warts around the nails have a tendency to develop into squamous cell cancer," she tells WebMD. "If patients see a dark discoloration involving the cuticle, then we worry about melanoma," the deadliest form of skin cancer.
Fox advises reporting these types of changes to a specialist as soon as possible. "Dermatologists are well-trained in deciphering between innocuous and serious nail conditions, as well as determining when a change requires further testing."