Skip to content
    Font Size
    A
    A
    A

    Polycystic Liver Disease: Symptoms, Causes, and Treatment

    Polycystic liver disease (PLD or PCLD) is a rare condition that causes cysts -- fluid-filled sacs -- to grow throughout the liver. A normal liver has a smooth, uniform appearance. A polycystic liver can look like a cluster of very large grapes. Cysts also can grow independently in different parts of the liver. The cysts, if they get too numerous or large, may cause discomfort and health complications. But most people with polycystic liver disease do not have symptoms and live a normal life.

    Here are the facts about polycystic liver disease you need to better understand the condition.

    Recommended Related to Digestive Disorders

    Water: A Fluid Way to Manage Constipation

    Chronic constipation -- when you can’t poop -- is a common digestive problem. You might have considered over-the-counter laxatives to “get things moving,” but you can do plenty to manage chronic constipation without taking medicine. One of the simplest ways is to drink plenty of fluids every day, eat dietary fiber, and exercise.

    Read the Water: A Fluid Way to Manage Constipation article > >

    What Causes Polycystic Liver Disease?

    The majority of people with polycystic liver disease inherit the condition, but PLD can occur randomly with no genetic link. Women are affected more often than men and tend to have more cysts.

    PLD is most common in people who have polycystic kidney disease (PCKD), with its frequency increasing with age and advanced renal disease.

    Most people don't discover they have PLD until they are adults, when the cysts become large enough to detect. Cysts can vary in size from no bigger than a pinhead to almost 4 inches wide. Likewise, your liver can stay its normal size or become extremely enlarged. No matter the number or size of cysts, polycystic livers continue to function normally and the disease is not considered life threatening.

    Because it's inherited, if you or someone in your immediate family has PLD, other family members should be tested for it. Doctors can diagnose polycystic liver disease with imaging studies, such as ultrasound, CT scan, or MRI.

    What Are the Symptoms of Polycystic Liver Disease?

    Most of the time, people with polycystic liver disease have no symptoms. However, if the liver becomes enlarged and riddled with cysts, symptoms may include:

    Only about one out of every 10 people with PLD has problems associated with it. In addition to severe abdominal pain, other complications may include:

    • Bleeding into a cyst
    • Infection of a cyst
    • Bile duct obstruction and jaundice (yellowing of the skin and eyes)

    1 | 2 | 3

    Today on WebMD

    man holding his stomach
    Get the facts on common problems.
    blueberries in a palm
    Best and worst foods.
     
    woman shopping
    Learn what foods to avoid.
    fresh and dried plums
    Will it help constipation?
     
    diverticuliltis illustration
    Slideshow
    couple eating at cafe
    Article
     
    sick child
    Slideshow
    Woman blowing bubble gum
    Slideshow
     

    Send yourself a link to download the app.

    Loading ...

    Please wait...

    This feature is temporarily unavailable. Please try again later.

    Thanks!

    Now check your email account on your mobile phone to download your new app.

    Woman with crohns in pain
    Slideshow
    Woman with stomach pain
    Slideshow
     
    diet for diverticulitis
    Video
    what causes diarrhea
    Video