What should I Know Regarding Pregnancy, Nursing and Administering Invokana to Children or the Elderly?

If you are PREGNANT

  • Not Recommended: INSUFF HUMAN DATA AVAIL; ANIMAL DATA SHOW DEVELOPMENTAL TOXICITY IN 2ND/3RD TRIM

If you are NURSING

  • Precaution: INSUFF HUMAN DATA; EXCRETED IN RATS, DATA SUGGEST RISK TO KIDNEY DEVELOPMENT

If you are an adult over 60

  • management or monitoring precaution: Cardiovascular-Reduced intravascular volume increased risk of hypotension, dizziness, dehydration. Renal-Renal toxicity increases with hypovolemia, CHF. Evaluate renal function prior to initiation and monitor periodically. Dosage adjustment recommended with eGFR<60 mL/min/1.73 m2. Not recommended with persistent eGFR <45 mL/min/1.73 m2 and is contraindicated with eGFR<30 mL/min/1.73 m2. Musculoskeletal-Monitor bone mineral density in osteopenia/osteoporosis. Bone fractures have occurred.

Giving Invokana to a child under 12

  • management or monitoring precaution: No safety and efficacy established in pediatrics.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.