Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Voriconazole may slow down how quickly your liver processes omeprazole.
What might happen:
The amount of omeprazole in your blood may increase and cause side effects.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to change your dose of omeprazole while you are taking voriconazole. Let your doctor know if you develop headaches, diarrhea, gas, constipation, stomach/abdominal pain, unusual tiredness, dizziness, or vomiting.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.Reference:1.Vfend (voriconazole) US prescribing information. Pfizer Inc. November, 2011.