Infrequently, iron dextran for injection has caused severe (sometimes fatal) allergic reactions. It should be used only when clearly needed and when a patient is unable to take iron by mouth (oral forms).Who should not take iron dextran injection?
This medication is used to treat "iron-poor" blood (anemia) in people who cannot take iron by mouth because of side effects or because their anemia has not been successfully treated by it. Low iron levels can occur when the body can't get enough iron from food (poor nutrition, poor absorption) or when there is a large or long-term blood loss (e.g., hemophilia, stomach bleeding). You may also need extra iron because of blood loss during kidney dialysis. Your body may need more iron if you use the drug erythropoietin to help make new red blood cells.
Iron is an important part of your red blood cells and is needed to carry oxygen in the body.
This medication is usually injected deep into the muscle of the buttock or slowly into a vein as directed by your doctor. When injecting into the buttock, the next injection is given on the opposite side from the last injection.
Before the first full dose, a smaller test dose is given slowly to check for possible allergic effects. If no reaction is seen after one hour, the full dose may be given. You will be checked carefully for reactions by a health care worker each time you are getting the iron.
Iron injections may be given once daily in small doses or as directed by your doctor. Large doses may be given in a solution and injected into a vein over several hours. Some side effects such as dizziness and flushing may be stopped by giving the drug more slowly. The dose and length of treatment is based on your age, weight, condition, and response to therapy. Your doctor will order blood tests to monitor your response.
If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.
Flushing, tingling of the hands/feet, shivering, or dizziness may occur. The area around the injection site may be tender, irritated, or discolored (brown). If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
Some people may experience a delayed reaction 1-2 days after their treatment. These side effects usually lessen within 3 to 4 days if the medication was injected into a vein or within 3 to 7 days if the medication was injected into a muscle. Tell your doctor if any of these side effects persist or worsen more than 4 to 7 days after your treatment: back/joint/muscle aches, chills, moderate to high fever, headache, nausea/vomiting.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug may occur. Get medical help right away if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Before using this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: low blood count not due to low iron (e.g., vitamin B12/folate deficiency), active kidney infection.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe allergic reactions, asthma, bleeding problems (e.g., hemophilia), heart disease (e.g., chest pain, heart attack, heart failure), Hodgkin's disease, autoimmune disease (e.g., rheumatoid arthritis, ankylosing spondylitis, lupus), kidney disease/dialysis, liver disease.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with this drug include: other iron products.
This medication may interfere with certain laboratory tests (including bilirubin, calcium, and clotting times), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.
Laboratory and/or medical tests (e.g., complete blood count, iron) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
It is important to maintain a well-balanced diet to ensure adequate intake of iron, vitamins, and minerals. Good sources of iron include meats (especially liver), eggs, raisins, figs, broccoli, Brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Follow any diet recommendations given to you by your doctor.
For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule. Do not double the dose to catch up.
Consult the product instructions and your pharmacist for storage details. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised March 2014. Copyright(c) 2014 First Databank, Inc.
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