Erectile Dysfunction Health Center
Drugs Linked to Erectile Dysfunction
If you are having problems achieving or maintaining an erection you may want to take a look at your medicine cabinet. There are a number of prescription and over-the-counter drugs that may cause erectile dysfunction. While these medications may treat a disease or condition, in doing so they can affect a man's hormones, nerves, or blood circulation, resulting in ED or increase the risk of ED.
Examples of medicines that may cause ED are listed below. The list of possible offenders is long, however, so check with your doctor about all medications you are taking to rule out any as a cause of, or contributor to, your ED.
If you experience ED and think that it may be a result of medication you are taking, do not stop taking the medication without first consulting your doctor. If the problem persists, your doctor may be able to prescribe a different medication.
Other substances or drugs that can cause or lead to ED include recreational and frequently abused drugs, such as:
- Alcohol
- Amphetamines
- Barbiturates
- Cocaine
- Marijuana
- Methadone
- Nicotine
- Opiates
Aside from the well-known complications that the use and abuse of these drugs can cause, ED is not often mentioned. However, use of these drugs can cause ED. These drugs not only affect and often times suppress the central nervous system, but can also cause serious damage to the blood vessels, resulting in permanent ED.
Reviewed by the doctors at the Glickman Urological Institute at The Cleveland Clinic.
WebMD Medical Reference provided in collaboration with the Cleveland Clinic![]()
Indication
Uroxatral® (alfuzosin HCl 10 mg extended-release tablets) is an alpha1-blocker for the treatment of the signs and symptoms of BPH.
Important Safety Information
Do not take UROXATRAL if you have liver problems or if you are taking antifungal drugs like ketoconazole or itraconazole, or HIV drugs like ritonavir.
UROXATRAL can cause a sudden drop in blood pressure, especially when starting treatment. This may lead to fainting, dizziness, and lightheadedness. Do not drive, operate machinery, or do any dangerous activity until you know how UROXATRAL will affect you. This is especially important if you already have a problem with low blood pressure or take medicines to treat high blood pressure. There may be an increased risk of low blood pressure and fainting when taking UROXATRAL in combination with blood pressure medication or nitrates, or erectile dysfunction medication.
If considering cataract surgery (clouding of the eyes), tell your eye surgeon that you are currently taking UROXATRAL or have previously been treated with an alpha-blocker.
Before taking UROXATRAL, tell your doctor if you have kidney problems.
Also, tell your doctor if you or any family member(s) have or take medications for a rare heart condition known as congenital prolongation of the QT interval.
BPH and prostate cancer can cause the same symptoms. However, UROXATRAL is not a treatment for prostate cancer.
The most common side effects with UROXATRAL are dizziness, upper respiratory tract infection, headache, and tiredness.
Please see UROXATRAL full prescribing information.



