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Complications of Mitral Valve Prolapse

Complications of mitral valve prolapse (MVP) are not common. Most people with MVP do not have significant problems and do not need treatment. Complications of MVP develop mostly in people who have:

  • A mitral valve murmur during contraction (systole).
  • Thickened mitral valve flaps (leaflets).
  • An enlarged upper left heart chamber (atrium) or lower left heart chamber (ventricle).

Complications of MVP include:

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  • Mitral valve regurgitation, which is the most common complication.
  • Infection of the valve and lining of the heart (endocarditis).
  • Irregular or rapid heart rhythm (arrhythmia).
  • Temporary interruption of blood flow to an area of the brain (transient ischemic attack, or TIA) or a stroke (mainly in those who have atrial fibrillation).
  • Heart failure, if mitral valve regurgitation develops.
By Healthwise Staff
Primary Medical Reviewer E. Gregory Thompson, MD - Internal Medicine
Specialist Medical Reviewer John A. McPherson, MD, FACC, FSCAI - Cardiology
Last Revised January 20, 2011

WebMD Medical Reference from Healthwise

Last Updated: January 20, 2011
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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