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Human Immunodeficiency Virus (HIV) Infection - What Happens

There are two types of HIV:

  • HIV-1, which causes almost all the cases of AIDS worldwide
  • HIV-2, which causes an AIDS-like illness. HIV-2 infection is uncommon in the United States.

How the disease is spread

HIV is spread when blood, semen, or vaginal fluids from an infected person enter another person's body, usually through:

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  • Sexual contact. The virus may enter the body through a tear in the lining of the rectum, vagina, urethra, or mouth. About 80% of all cases of HIV are transmitted by sexual contact.3
  • Infected blood. HIV can be spread when a person:
    • Shares needles, syringes, cookers, cotton, cocaine spoons, or eyedroppers used for injecting drugs or steroids.
    • Is accidentally stuck with a needle or other sharp item that is contaminated with HIV.

It is now extremely rare in the United States for HIV to be transmitted by blood transfusions or organ transplants. Blood and organ donors are screened for risk factors. All donated blood and organs are screened for HIV.

Spread of HIV to babies

A woman who is infected with HIV can spread the virus to her baby during pregnancy, delivery, or breast-feeding.

  • Most children younger than 13 years who have HIV were infected with the virus by their mothers.
  • The risk of a woman spreading HIV to her baby can be greatly reduced if she is on medicine that reduces her viral load (HIV RNA) to undetectable levels during pregnancy, if she receives AZT (ZDV) before the baby is born, and if she does not breast-feed her baby. The baby should also receive treatment after it is born. Treatment of a baby shortly after birth greatly reduces the chance that the baby will die from the HIV infection.4

Ways HIV cannot be spread

HIV does not survive well outside the body. So HIV cannot be spread through casual contact with an infected person, such as by sharing drinking glasses or by casual kissing. HIV is not transmitted through contact with an infected person's saliva, sweat, tears, urine, or feces, or through insect bites.

Contagious and incubation period

The incubation period-the time between when a person is first infected with HIV and when early symptoms develop-may be a few days to several weeks.

It can take as little as 2 weeks or as long as 6 months from the time you become infected with HIV for the antibodies to be detected in your blood. This is commonly called the "window period," or seroconversion period. During the window period, you are contagious and can spread the virus to others. If you think you have been infected with HIV but you test negative for it, you should be tested again. Tests at 6, 12, and 24 weeks can be done to be sure you are not infected.

WebMD Medical Reference from Healthwise

Last Updated: October 17, 2011
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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