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    Hypertension/High Blood Pressure Health Center

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    Other Medicines for High Blood Pressure

    Examples

    Alpha-adrenergic blockers (alpha-blockers)

    Generic Name Brand Name
    doxazosin Cardura
    prazosin Minipress
    terazosin Hytrin

    Central alpha-adrenergic agonists

    Generic Name Brand Name
    clonidine Catapres

    Direct vasodilators

    Generic Name
    hydralazine
    minoxidil

    How It Works

    These medicines lower high blood pressure by opening up (dilating) the blood vessels. This allows blood to flow more easily, which lowers blood pressure.

    Some of these medicines need to be combined with other medicines to counteract the body's natural tendency to retain fluid and increase heart rate when there is a sudden drop in blood pressure.

    Why It Is Used

    These drugs often are used in combination with other drugs to treat high blood pressure when first-line medicines alone do not control blood pressure. They might be used if a person is in a hypertensive crisis.

    These medicines are used to treat other health problems, too.

    How Well It Works

    These medicines are effective in helping reduce blood pressure. They are usually not used as the first medicine but are added on to other therapies.1

    Side Effects

    All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.

    Here are some important things to think about:

    • Usually the benefits of the medicine are more important than any minor side effects.
    • Side effects may go away after you take the medicine for a while.
    • If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Do not suddenly quit taking your medicine unless your doctor tells you to.

    Call911or other emergency services right away if you have:

    Call your doctor if you have:

    Common side effects include:

    See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

    What To Think About

    For tips on taking blood pressure medicine, see:

    actionset.gif High Blood Pressure: Taking Medicines Properly.

    Taking medicine

    Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.

    There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.

    Advice for women

    If you are pregnant, breast-feeding, or planning to get pregnant, do not use any medicines unless your doctor tells you to. Some medicines can harm your baby. This includes prescription and over-the-counter medicines, vitamins, herbs, and supplements. And make sure that all your doctors know that you are pregnant, breast-feeding, or planning to get pregnant.

    Checkups

    Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.

    Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.

    Citations

    1. Drugs for hypertension (2012). Treatment Guidelines From The Medical Letter, 10(113): 1-10.

    ByHealthwise Staff
    Primary Medical ReviewerE. Gregory Thompson, MD - Internal Medicine
    Specialist Medical ReviewerRobert A. Kloner, MD, PhD - Cardiology

    Current as ofMarch 12, 2014

    WebMD Medical Reference from Healthwise

    Last Updated: March 12, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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