Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Font Size

New Debate on Human Test of Stem Cells

Scientists Wrestle With Risks and Benefits of Implanting Stem Cells in People
WebMD Health News

April 10, 2008 -- While politicians battle over where to set limits for human embryonic stem cell studies, regulators are mulling where it should set scientific limits on the promising but controversial research.

Despite widespread media coverage, embryonic stem cells and related cells have only been implanted in a handful of human patients. Researchers say some of the experiments have shown early signs of success. Others have been failures because they were ineffective or led to tumors.

Most research is still conducted in Petri dishes and animals like rats and pigs. But with the field on the brink of producing new therapies for humans, how to test those treatments -- and how much risk to tolerate -- remain open questions.

Stem cells' scientific promise lies in their ability to form dozens of different tissues in the body. As these cells divide and grow, they can be coaxed to form heart, lung, brain, or pancreatic cells. That makes them good candidates to engineer new tissues to repair diseases or injuries.

But their potential may also be a curse. Because embryonic stem cells are genetically programmed to easily divide and grow, research shows they also have the propensity to form tumors.

Cancer and Stem Cells

Scientists and regulators now see a narrow path for the research: designing stem cell studies bold enough to find successful treatments without overreaching and causing cancer.

"We are really in uncharted water," said Stanton L. Gerson, MD, a professor of medicine at Case Western Reserve University in Cleveland and a member of an FDA advisory panel on stem cell research that met outside Washington, D.C. on Thursday.

Research in animals has already shown that high doses of stem cells are ideal for guaranteeing enough cells will survive, reproduce, and grow into new tissue once they're in the body. The cells also grow much more readily if they are implanted at a very early stage, before they differentiate.

But many studies also show that higher doses of more primitive cells are the very ones likely to produce tumors.

So experts and regulators are now wrestling with what kinds of safety cushions researchers should show in animals before the FDA lets the experiments proceed in humans in years to come.

WebMD Video: Now Playing

Click here to wach video: Dirty Truth About Hand Washing

Which sex is the worst about washing up? Why is it so important? We’ve got the dirty truth on how and when to wash your hands.

Click here to watch video: Dirty Truth About Hand Washing