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    Prostate Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

    Stage I Prostate Cancer

    Standard treatment of stage I prostate cancer may include the following:

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    Treatment for Advanced Prostate Cancer

    If you have an advanced stage of prostate cancer (stage III and IV), it means the disease has spread outside your prostate gland. Doctors can treat this type of cancer, but they can’t cure it. Still, there are good options that can ease your symptoms and help you live a long, active life. Talk with your doctor about the treatment that’s best for you. Ask him about the kinds of side effects you might have. You’ll want to choose a path that gives you the best results with the fewest risks. Your ...

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    • Watchful waiting.
    • Active surveillance. If the cancer begins to grow, hormone therapy may be given.
    • Radical prostatectomy, usually with pelvic lymphadenectomy. Radiation therapy may be given after surgery.
    • External-beam radiation therapy. Hormone therapy may be given after radiation therapy.
    • Internal radiation therapy with radioactive seeds.
    • A clinical trial of high-intensity focused ultrasound.
    • A clinical trial of cryosurgery.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage I prostate cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    Stage II Prostate Cancer

    Standard treatment of stage II prostate cancer may include the following:

    • Watchful waiting.
    • Active surveillance. If the cancer begins to grow, hormone therapy may be given.
    • Radical prostatectomy, usually with pelvic lymphadenectomy. Radiation therapy may be given after surgery.
    • External-beam radiation therapy. Hormone therapy may be given after radiation therapy.
    • Internal radiation therapy with radioactive seeds.
    • A clinical trial of cryosurgery.
    • A clinical trial of high-intensity focused ultrasound.
    • A clinical trial of proton beam radiation therapy.
    • Clinical trials of new types of treatment, such as hormone therapy followed by radical prostatectomy.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II prostate cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    Stage III Prostate Cancer

    Standard treatment of stage III prostate cancer may include the following:

    • External-beam radiation therapy. Hormone therapy may be given after radiation therapy.
    • Hormone therapy.
    • Radical prostatectomy. Radiation therapy may be given after surgery.
    • Watchful waiting.
    • Active surveillance. If the cancer begins to grow, hormone therapy may be given.
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