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Prostate Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

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Stage III Prostate Cancer

Standard treatment of stage III prostate cancer may include the following:

  • External-beam radiation therapy. Hormone therapy may be given after radiation therapy.
  • Hormone therapy.
  • Radical prostatectomy. Radiation therapy may be given after surgery.
  • Watchful waiting.
  • Active surveillance. If the cancer begins to grow, hormone therapy may be given.

Treatment to control cancer that is in the prostate and lessen urinary symptoms may include the following:

  • External-beam radiation therapy.
  • Internal radiation therapy with radioactive seeds.
  • Hormone therapy.
  • Transurethral resection of the prostate (TURP).
  • A clinical trial of new types of radiation therapy.
  • A clinical trial of cryosurgery.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage III prostate cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Stage IV Prostate Cancer

Standard treatment of stage IV prostate cancer may include the following:

  • Hormone therapy.
  • Bisphosphonate therapy.
  • External-beam radiation therapy. Hormone therapy may be given after radiation therapy.
  • Watchful waiting.
  • Active surveillance. If the cancer begins to grow, hormone therapy may be given.
  • A clinical trial of radical prostatectomy with orchiectomy.

Treatment to control cancer that is in the prostate and lessen urinary symptoms may include the following:

  • Transurethral resection of the prostate (TURP).
  • Radiation therapy.

Treatment to control pain from cancer that has spread to the bone may include the following:

  • Pain medicine.
  • External-beam radiation therapy.
  • Internal radiation therapy with radioisotopes such as strontium-89.
  • Targeted therapy with a monoclonal antibody.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IV prostate cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

WebMD Public Information from the National Cancer Institute

Last Updated: September 04, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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