Skip to content
My WebMD Sign In, Sign Up

Find a Vitamin or Supplement

PANTETHINE

Other Names:

Bis-pantothenamidoethyl disulfide, D-bis-(N-Pantothenyl-B-aminoethyl)-disulfide, D-Pantethine, D-Pantéthine, Pantéthine, Pantetheine, Pantethine Octahydrate, Pantetina, Pantomin, Pantosin.

PANTETHINE Overview
PANTETHINE Uses
PANTETHINE Side Effects
PANTETHINE Interactions
PANTETHINE Dosing
PANTETHINE Overview Information

Pantethine is a dietary supplement that is related to vitamin B5 (pantothenic acid).

Pantethine is used for lowering cholesterol, preventing inflammation, boosting the activity of the immune system, treating an inherited condition called cystinosis, treating gastrointestinal (GI) diseases, and improving athletic performance. It is also used for improving energy, lowering the risk of heart attack and stroke, improving adrenal function, protecting against mental and physical stress, and preventing allergy symptoms in people who are allergic to formaldehyde.

How does it work?

Pantethine might increase the concentrations of chemicals that lower blood cholesterol and triglycerides.

PANTETHINE Uses & Effectiveness What is this?

Possibly Effective for:

  • Lowering blood fats such as cholesterol and triglycerides, but only modestly. While not all research findings agree, taking pantethine might slightly lower triglycerides, total cholesterol, and “bad” low-density lipoprotein (LDL) cholesterol; as well as raise “good” high-density lipoprotein (HDL) cholesterol. Pantethine also appears to correct blood fat problems that often occur in kidney failure patients who are undergoing hemodialysis.

Insufficient Evidence for:

  • Treating cystinosis, an inherited disease. Early research suggests that pantethine might be beneficial for cystinosis.
  • Improving athletic performance. Some research suggests that pantethine in combination with pantothenic acid and thiamine (given as allithiamin) does not improve muscular strength or endurance in well-trained athletes.
  • Reducing risk of heart and circulatory disease.
  • Improving function of the adrenal gland.
  • Preventing allergy symptoms in people allergic to formaldehyde.
  • Other conditions.
More evidence is needed to rate the effectiveness of pantethine for these uses.


PANTETHINE Side Effects & Safety

Taking pantethine appears to be safe for most people for up to a year. Pantethine can cause nausea, diarrhea, and stomach discomfort.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of pantethine during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Bleeding disorders: There is some evidence that pantethine can slow blood clotting, so some healthcare providers worry that pantethine might increase the risk of severe bleeding in patients with bleeding disorders. If you have a bleeding disorder, get your healthcare provider’s advice before starting pantethine.

Surgery: Pantethine might slow blood clotting. There is a concern that it might increase the risk of extra bleeding during and after surgery. Stop using pantethine at least 2 weeks before a scheduled surgery.

PANTETHINE Interactions What is this?

Moderate Interaction Be cautious with this combination

  • Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with PANTETHINE

    Pantethine might slow blood clotting. Taking pantethine along with medications that also slow clotting might increase the chances of bruising and bleeding.
    Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.


PANTETHINE Dosing

The following doses have been studied in scientific research:

BY MOUTH:

  • For treating too much fat in the blood (hyperlipoproteinemia): 300 mg of pantethine 3 to 4 times daily.

See 10 Reviews for this Treatment - OR -

Review this Treatment

Learn about User Reviews and read IMPORTANT information about user generated content

Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009.

Search for a Vitamin or Supplement

Ex. Ginseng, Vitamin C, Depression

Today on WebMD

Woman taking a vitamin or supplement
Article
Man taking a vitamin or supplement
Article
 
clams
Quiz
Woman in sun
Slideshow
 
Flaxseed added fiber
Video
!!69X75_Vitamins_Supplements.jpg
Evaluator
 
Woman sleeping
Article
Woman staring into space with coffee
Article
 
IMPORTANT: About This Section and Other User-Generated Content on WebMD

The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment.

Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.