RUTIN Overview Information
Rutin is a plant pigment (flavonoid) that is found in certain fruits and vegetables. Rutin is used to make medicine. The major sources of rutin for medical use include buckwheat, Japanese pagoda tree, and Eucalyptus macrorhyncha. Other sources of rutin include the leaves of several species of eucalyptus, lime tree flowers, elder flowers, hawthorn leaves and flowers, rue, St. John's Wort, Ginkgo biloba, apples, and other fruits and vegetables.
Some people believe that rutin can strengthen blood vessels, so they use it for varicose veins, internal bleeding, hemorrhoids, and to prevent strokes due to broken veins or arteries (hemorrhagic strokes). Rutin is also used to prevent a side effect of cancer treatment called mucositis. This is a painful condition marked by swelling and ulcer formation in the mouth or lining of the digestive tract.
In combination with the proteins trypsin and bromelain, rutin is also used for osteoarthritis.
How does it work?
Rutin has chemicals that might offer some protection against cancer.
RUTIN Uses & Effectiveness 
Possibly Effective for:
- Osteoarthritis when taken in combination with trypsin and bromelain. This combination seems to be about as effective as the medicationdiclofenac (Voltaren) in relieving pain and improving knee function in people with osteoarthritis.
Insufficient Evidence for:
- Blood vessel disease.
- Varicose veins.
- Prevention of mouth ulcers associated with cancer treatments.
- Bleeding.
- Hemorrhoids.
RUTIN Side Effects & Safety
Rutin is LIKELY SAFE when used in food amounts and POSSIBLY SAFE when used appropriately in medicinal amounts for a short period of time. It can cause some side effects including headache, flushing, rashes, or stomach upset.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Not enough is known about the use of rutin during pregnancy and breast-feeding. Stay on the safe side and avoid use.RUTIN Dosing
The following doses have been studied in scientific research:
BY MOUTH:
- For osteoarthritis: 2 tablets of a combination product (Phlogenzym), which contains 100 mg of rutin, 48 mg of trypsin, and 90 mg of bromelain, 3 times daily.






