Who should not take ORAP?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:

Conditions:

  • breast cancer
  • a high prolactin level
  • low amount of magnesium in the blood
  • low amount of potassium in the blood
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • chronic muscle twitches or movements
  • a type of movement disorder called parkinsonism
  • tardive dyskinesia, a disorder characterized by involuntary movements of the face, mouth and tongue
  • extrapyramidal disease, a type of movement disorder
  • neuroleptic malignant syndrome, a reaction characterized by fever, muscle rigidity and confusion
  • glaucoma, an increased pressure in the eye
  • torsades de pointes, a type of abnormal heart rhythm
  • prolonged QT interval on EKG
  • abnormal heart rhythm
  • ventricular arrhythmias, a type of abnormal heart rhythm
  • abnormal EKG with QT changes from birth
  • liver problems
  • decreased kidney function
  • enlarged prostate
  • coma
  • seizures
  • an inability to completely empty the bladder
  • impairment of central nervous system due to medication
  • dementia in an elderly person
  • CYP2D6 poor metabolizer

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.