Who should not take Extra Strength Pain Reliever Tablet?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • caloric undernutrition
  • acute liver failure
  • liver problems
  • severe renal impairment
  • Shock
  • acetaminophen overdose
  • Acute Inflammation of the Liver due to Hepatitis C Virus
  • high blood pressure
  • heart attack within the last 30 days
  • abnormal heart rhythm
  • ulcer from stomach acid
  • inflamed colon and small intestine with some tissue death
  • severe liver disease
  • seizures
  • chronic trouble sleeping
  • moderate to severe kidney impairment
  • systemic mastocytosis
  • inadequate vitamin K
  • gout
  • anemia
  • hemophilia
  • decrease in the blood-clotting protein prothrombin
  • Blood Clotting Disorder - Von Willebrand's Disease
  • decreased blood platelets
  • alcoholism
  • Reye's syndrome
  • thrombotic thrombocytopenic purpura
  • Presence of Polyps in the Nose
  • stomach or intestinal ulcer
  • damage to stomach lining
  • bleeding of the stomach or intestines
  • kidney disease with reduction in kidney function
  • pregnancy
  • a mother who is producing milk and breastfeeding
  • Anemia from Pyruvate Kinase and G6PD Deficiencies
  • aspirin exacerbated respiratory disease


  • Xanthines
  • Coffee
  • Guarana
  • Salicylates
  • NSAIDS (Non-Steroidal Anti-Inflammatory Drug)
  • Aspirin (Tartrazine Only)
  • Acetaminophen

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.