Felodipine; Nisoldipine/Itraconazole; Ketoconazole Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Very Serious. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Your antifungal may decrease the ability of your liver to remove felodipine and nisoldipine from your body.
What might happen:
The amount of felodipine or nisoldipine in your body may cause your blood pressure to decrease too much. Symptoms of low blood pressure include: dizziness, light-headedness, irregular heartbeat, nausea, drowsiness, confusion, and slurred speech. You may also notice a headache or swelling in your legs and/or feet.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know right away that you are taking these medicines together. Your doctor may want to decrease the dose of your felodipine or nisoldipine, change to a different blood pressure medicine, or change your antifungal medicine. Let your doctor know right away if you develop any signs of low blood pressure, a decreased heart rate, or swelling of the legs.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.