Alipogene Tiparvovec/Anticoagulant;Antiplatelet;Thrombolytic Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

During an alipogene tiparvovec treatment session you will receive 27 - 60 injections in your leg muscles.Anticoagulant (e.g. warfarin), antiplatelet (e.g. aspirin, clopidogrel) or thrombolytic medicines decrease your body's ability to make clots.

What might happen:

If you take a medicine that decreases the ability of your blood to clot, you could have bleeding or bruising at injection sites.

What you should do about this interaction:

Before receiving alipogene tiparvovec, make sure to inform your doctor and healthcare professionals of all the medicines you are taking, especially if: you are taking any prescription or nonprescription for pain, inflammation or fever; if you are taking any medicines that can affect blood clotting (e.g. aspirin, clopidogrel, warfarin and others) because many of these medicines can affect blood clotting. Your doctor will want to stop medicines which can decrease blood clotting for 7 days before receiving alipogene tiparvovec and for one or more days after treatment.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Glybera (alipogene tiparvovec) Europe Medicines Agency SPC. accessed at: http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicine s/002145/human_med_001480.jsp&mid=WC0b01ac058001d124 June 26, 2015..

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.