Who should not take Savella?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • Syndrome of Inappropriate Antidiuretic Hormone Secretion
  • low amount of sodium in the blood
  • increased risk of bleeding
  • Behaving with Excessive Cheerfulness and Activity
  • Mild Degree of Mania
  • Suicidal
  • Habit of Drinking Too Much Alcohol
  • serotonin syndrome - adverse drug interaction
  • closed angle glaucoma
  • high blood pressure
  • Sinus Tachycardia
  • Liver Problems
  • Urinary Tract Blockage
  • seizures
  • Abnormal Liver Function Tests
  • risk of angle-closure glaucoma due to narrow angle of anterior chamber of eye
  • chronic kidney disease stage 4 (severe)
  • chronic kidney disease stage 5 (failure)


  • Milnacipran Analogues