Who should not take Savella?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • syndrome of inappropriate antidiuretic hormone secretion
  • low amount of sodium in the blood
  • increased risk of bleeding
  • behaving with excessive cheerfulness and activity
  • mild degree of mania
  • having thoughts of suicide
  • alcoholism
  • serotonin syndrome - adverse drug interaction
  • closed angle glaucoma
  • high blood pressure
  • sinus tachycardia
  • liver problems
  • urinary tract blockage
  • seizures
  • abnormal liver function tests
  • risk of angle-closure glaucoma due to narrow angle of anterior chamber of eye
  • chronic kidney disease stage 4 (severe)
  • chronic kidney disease stage 5 (failure)


  • Milnacipran Analogues

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.