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    Xgeva Vial

    precautions

    What should I know regarding pregnancy, nursing and administering Xgeva Vial to children or the elderly?

    If you are:

    Pregnant:

    Not Recommended: CROSSES PLACENTA WITH LARGEST TRANSFER IN 3RD TRIM; ANIMAL DATA SUG DEV TOX

    Nursing:

    Precaution: INSUFFICIENT HUMAN DATA AVAILABLE

    An adult over 60:

    management or monitoring precaution: General-Monitor serum calcium closely. Increased risk of hypocalcemia with creatinine clearance less than 30 mL/min or on dialysis. Supplement calcium and vitamin D as needed. Musculoskeletal-Reports of atypical, pathologic subtrochanteric or proximal diaphyseal fractures can occur with little or no trauma.

    Giving Xgeva Vial to a child under 12:

    Severe Precaution: Potential risk of impaired bone growth and tooth development. Limited use for giant cell tumor of bone in skeletally mature adolescents.

    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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